Efficacy of adjuvant mitomycin-C and triamcinoloneimpregnated nasal packing for endoscopic dacryocystorhinostomy  

作　　者：Sang Yoon Kim Christopher B Chambers Jung Hyo Ahn 

机构地区：[1]Department of Ophthalmology,Pusan National University Yangsan Hospital,Pusan National University School of Medicine,Research Institute for Convergence of Biomedical Science and Technology,Yangsan,Gyeongnam 50612,Republic of Korea [2]Department of Ophthalmology,Harborview Medical Center,University of Washington Medicine,Seattle,Washington 98109,USA

出　　处：《International Journal of Ophthalmology(English edition)》2024年第3期480-484,共5页国际眼科杂志（英文版）

摘　　要：●AIM:To compare the success rate and complications of adjuvant use of mitomycin C and triamcinoloneimpregnated biodegradable nasal packing(TABP)in endoscopic dacryocystorhinostomy(DCR).And to evaluate the efficacy of combining intraoperative mitomycin C and TABP for endoscopic DCR.●METHODS:A total of 198 eyes of 148 patients who underwent endoscopic DCR for acquired nasolacrimal duct obstruction were retrospectively analysed.The patients were randomly divided into three groups:Group A included patients treated without intraoperative mitomycin C but with TABP,Group B included patients treated without triamcinolone but with intraoperative mitomycin C and normal saline-impregnated nasal packing,and Group C included patients treated with intraoperative mitomycin C and TABP.●RESULTS:The results revealed no significant difference in the overall success rates between Groups A(86.8%)and B(89.2%;P=0.377).However,Group C(97.5%)showed a significantly higher overall success rate than Groups A and B.The incidence of granulomas was significantly lower in group C(5%)than in Groups A(20.8%)and B(15.2%;P=0.009).Other complications,such as crust,synechiae,and revision surgery,did not differ significantly among the three groups.●CONCLUSION:The combination of intraoperative mitomycin C and TABP effectively prevents granulomas and enhances surgical success rate.Additionally,there is no statistically significant difference observed between the use of mitomycin C or TABP alone.

关 键 词：DACRYOCYSTORHINOSTOMY endoscopic mitomycin C TRIAMCINOLONE biodegradable 

分 类 号：R765[医药卫生—耳鼻咽喉科]