基于神经调控的慢性疼痛治疗方法介绍  

Introduction to Neuromodulation-Based Therapies for Chronic Pain

作　　者：吴文[1] WU Wen(Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510282,China)

机构地区：[1]南方医科大学珠江医院,广东广州510282

出　　处：《康复学报》2024年第1期1-7,14,共8页Rehabilitation Medicine

基　　金：国家自然科学基金项目(82372553,82172526);广东省基础与应用基础研究基金面上项目(2021A1515011042)。

摘　　要：随着人口老龄化发展,慢性疼痛已成为严重的公共卫生问题。长期依赖药物治疗面临依赖性和毒副作用的困境。基于神经调控的非药物干预治疗为改善此情况提供了新思路。本文首先阐明慢性疼痛的现状及药物治疗的局限,指出拓展神经调控治疗的必要性。然后详细讨论神经调控治疗机制、主要方法及临床应用情况。同时,文章介绍了治疗效果评估的关键指标,并分析目前治疗方法的优劣势。最后,文章归纳相关治疗手段及当前面临的问题和挑战,展望未来研究方向,旨在系统梳理基于神经调控的慢性疼痛治疗策略,为改善慢性疼痛患者预后质量提供借鉴。With the development of an aging population,chronic pain has become a serious public health issue.Long-term drug dependence faces the dilemma of addiction and side effects.Non-drug interventions based on neuromodulation provide new ideas to improve this situation.Herein,the current status of chronic pain and the limitations of drug therapy are first clarified,highlighting the need to expand neuromodulation therapies.The mechanism,main methods,and clinical applications of neuromodulation therapy are then discussed in detail.Meanwhile,key indicators for evaluating therapeutic effects are presented,and the strengths and weaknesses of current treatment methods are analyzed.Finally,current issues and challenges of relevant treatment methods are summarized,and possible future research directions are considered,aiming to systematically sort out neuromodulation-based chronic pain treatment strategies and provide references for improving the prognosis and quality of life of patients with chronic pain.

关 键 词：慢性疼痛 老龄化 神经调控 疗效评价 

分 类 号：R402[医药卫生—临床医学]