糖尿病足感染病原学及抗感染治疗研究进展  

Research progress on etiology and anti-infection treatment of diabetic foot infection

作　　者：翟筱涵 王爱红[1] 母义明[2] ZHAI Xiao-han;WANG Ai-hong;MU Yi-ming(Diabetes Center of People's Liberation Army(PLA),PLA Strategic Support Force Medical Center(The 306th Hospital of PLA),Beijing 100101,China;不详)

机构地区：[1]战略支援部队特色医学中心(原解放军第306医院)内分泌科,北京100101 [2]解放军总医院第一医学中心内分泌科,北京100853

出　　处：《中华医院感染学杂志》2024年第4期635-640,共6页Chinese Journal of Nosocomiology

基　　金：全军青年培养-拔尖基金资助项目(16QNP041)。

摘　　要：糖尿病足溃疡(DFUs)是糖尿病的一种严重并发症,与感染、截肢和死亡密切相关.糖尿病足溃疡感染(IDFU)是糖尿病患者住院的常见原因,约占糖尿病住院患者的25%,给家庭和社会带来沉重的负担.致病微生物的鉴别难度大且存在耐药性,使得IDFU的诊疗具有挑战性.因此,基于IDFU的流行病学和患者个体化的病原学分析,早期识别并及时、合理应用有效的抗菌药物是改善IDFU患者预后的关键措施.本文基于国内外已有文献,就IDFU的流行病学、病原学及抗感染治疗的相关研究进展进行综述,旨在为临床提供参考.Diabetic foot ulcers(DFUs)are a serious complication of diabetes mellitus and are strongly associated with infection,amputation,and death.Diabetic foot ulcer infections(IDFU)are a common cause of diabetes-re-lated hospitalizations,accounting for approximately 25%of diabetic hospitalizations and placing a heavy burden on families and society.The difficulty in identifying pathogenic microorganisms and the presence of drug resistance make the diagnosis and treatment of IDFU challenging.Therefore,early identification and timely and reasonable application of effective antibiotics based on IDFU epidemiology and patient-individualized pathogenetic analysis are key measures to improve the prognosis of patients with IDFU.Based on the existing literature at home and a-broad,this article reviews the relevant research progress on the epidemiology,pathogenesis,and anti-infection therapy of IDFU,aiming to provide clinical references.

关 键 词：糖尿病 糖尿病足溃疡 糖尿病足溃疡感染 病原学 流行病学 抗菌治疗 

分 类 号：R587.1[医药卫生—内分泌]