糖尿病足溃疡修复中外泌体miRNA作用机制的研究进展  

Research progress of miRNA in exosomes in the repair of diabetic foot ulcer

作　　者：王玉莹 阙华发[1] WANG Yuying;QUE Huafa(Department of Surgery of Traditional Chinese Medicine,Longhua Hospital Afiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院中医外科,200032

出　　处：《中国糖尿病杂志》2024年第2期141-144,共4页Chinese Journal of Diabetes

基　　金：国家自然科学基金(81774317);上海市卫健委临床重点专科建设项目(shslczdzk03801);上海市卫健委海派中医流派传承创新团队建设项目(2021LPTD-001)。

摘　　要：糖尿病足溃疡(DFU)是DM严重并发症。外泌体(Exos)携带的miRNA是DFU伤口闭合过程中血管生成的重要调节剂,在调节DFU进展中发挥重要作用。本文综述Exos中的miRNA在DFU修复中作用机制的研究进展。Diabetic foot ulcer(DFU)is a serious complication of diabetes mellitus.The miRNA carried by exosomes(Exos)is an important regulator of angiogenesis during wound closure in DFU,playing a crucial role in regulating the progression of DFU.This article reviews the research progress on the mechanism of miRNA in Exos in DFUrepair.

关 键 词：外泌体 糖尿病足溃疡 MIRNA 

分 类 号：R587.2[医药卫生—内分泌]