糖尿病创面愈合中巨噬细胞极化表观遗传学调控的研究进展  

Research progress in epigenetic regulation of macrophage polarity in diabetic wound healing

作　　者：许诏华 师建平[1] XU Zhaohua;SHI Jianping(Inmer Mongolia Medical University,Hohhot 010107,China)

机构地区：[1]内蒙古医科大学,呼和浩特010107

出　　处：《中国糖尿病杂志》2024年第2期145-148,共4页Chinese Journal of Diabetes

基　　金：内蒙古自然科学基金(2022MS08022、2022SHZR0236);内蒙古自治区第八批“草原英才”个人项目(CYYC80395)。

摘　　要：DM创面愈合是多种因素共同作用的结果,巨噬细胞M1型向M2型转化困难是影响创面愈合的关键因素。巨噬细胞生物学功能与表观遗传修饰密切相关。本文综述糖尿病创面愈合中巨噬细胞极化表观遗传学调控的研究进展。The wound healing in patients with DM is the result of multiple factors.The difficulty of macrophage M1 to M2 transformation is the key factor affecting wound healing.The biological function of macrophages is closely related to epigenetic modifications.This article reviews the research progress of macrophage polarization epigenetic regulation in diabetic wound healing.

关 键 词：糖尿病创面 表观遗传修饰 巨噬细胞 

分 类 号：R587.2[医药卫生—内分泌]