回春散联合地西泮片防治小儿热性惊厥52例临床观察  

Clinical observation on the prevention and treatment of 52 cases of fever convulsions in children with Huichun San(回春散)combined with Diazepam Tablets

作　　者：罗丽[1] 黄丽丽[1] 吴嘉莉[1] 徐灵均 LUO Li;HUANG Lili;WU Jiali;XU Lingjun(Emergency Department,Jiangxi Children’s Hospital,Nanchang,Jiangxi,330006,China)

机构地区：[1]江西省儿童医院急诊科,江西南昌330006

出　　处：《中医儿科杂志》2024年第1期54-57,共4页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察回春散联合地西泮片防治小儿热性惊厥(FS)的临床疗效。方法选取2021年9月至2022年8月就诊于江西省儿童医院急诊科,且首次发生FS的105例患儿作为研究对象,按照随机数字表法分为对照组53例和治疗组52例。对照组在常规退热治疗的基础上给予地西泮片口服,治疗组在对照组治疗方法的基础上给予回春散口服,2组均3 d为1个疗程。结果治疗组热退时间和单次热程口服地西泮片次数均少于对照组,2组比较,差异有统计学意义(P<0.05或P<0.01)。对照组总不良反应发生率为41.51%(22/53),治疗组为9.62%(5/52),2组比较,差异有统计学意义(P<0.05)。对照组复发率和复发例次率分别为35.85%(19/53),32.18%(25/87);治疗组分别为17.31%(9/52),15.63%(15/96)。2组复发率和复发例次率比较,差异均有统计学意义(P<0.05)。结论回春散联合地西泮片防治小儿FS疗效显著,能明显缩短退热时间,减少口服地西泮片次数,降低惊厥复发率,值得临床推广应用。Objective To observe the clinical efficacy of Huichun San(回春散)combined with Diazepam Tablets in the prevention and treatment of febrile seizures(FS)in children.Methods 105 pediatric patients who visited the emergency department of Jiangxi Children’s Hospital from September 2021 to August 2022 and experi-enced FS for the first time were selected as the study subjects.They were randomly divided into a control group of 53 cases and a treatment group of 52 cases using a random number table method.The control group was given oral Dia-zepam Tablets on the basis of routine antipyretic treatment,while the treatment group was given oral children Huichun San on the basis of the control group’s treatment method.The course of treatment for both groups was 3 days.The results showed that the time for fever relief and the number of times a single hot course of oral Diazepam Tablets was less in the treatment group than in the control group,and the difference between the two groups was statistically significant(P<0.05 or P<0.01).The total incidence of adverse reactions in the control group was 41.51%(22/53),while in the treatment group it was 9.62%(5/52).The difference between the two groups was statistically significant(P<0.05).The recurrence rate of the control group were 35.85%(19/53)and 32.18%(25/87),re-spectively;The treatment groups were 17.31%(9/52)and 15.63%(15/96),respectively.The difference in recur-rence rate and recurrence rate between the two groups was statistically significant(P<0.05).Conclusion The combination of Huichun San and Diazepam Tablets has a significant therapeutic effect on the prevention and treat-ment of pediatric FS.It can significantly shorten the fever relief time,reduce the number of oral Diazepam Tablets,lower the recurrence rate of seizures,and has high safety.It is worthy of clinical promotion and application.

关 键 词：小儿 热性惊厥 回春散 临床观察 

分 类 号：R272.6[医药卫生—中医儿科学]