Predictors of hemorrhagic manifestations in dengue:A prospective observational study from the Hadoti region of Rajasthan  

作　　者：Shiv Charan Jelia Devendra Ajmera Divya Airan Ranjeet Bairwa Yogesh Meena 

机构地区：[1]Department of General Medicine,Government Medical College,Kota,Rajasthan,India

出　　处：《Journal of Acute Disease》2023年第6期226-232,共7页急性病杂志（英文版）

摘　　要：Objective:To study the laboratory and clinical predictors of hemorrhagic manifestations in dengue virus-infected patients.Methods:This was a single-center hospital-based prospective observational study.200 Dengue seropositive patients were included in the study.A detailed clinical examination was done and comprehensive laboratory investigations were done.These parameters were compared between patients with and without hemorrhagic manifestations.Results:Out of the 200 patients,47(23.5%)had bleeding.64.5%Patients were males and 76.0%were under the age of 40 years.The most common presenting symptoms were fever(100.0%)followed by myalgia(77.0%),nausea and vomiting(56.0%).Leukocytosis,neutrophilia,thrombocytopenia,hyperbilirubinemia,transaminitis,decreased serum albumins,and raised D-dimer can serve as hematological,biochemical,and coagulation predictors of hemorrhagic manifestations for dengue.Conclusions:Dengue is a tropical infection with various complications.Bleeding complications are one of them.Laboratory parameters like white blood cells,platelets,bilirubin level,liver enzymes,and D-dimer can help to identify patients at risk for bleeding.Early identification and appropriate management can save a lot of resources and lives.

关 键 词：Dengue fever Dengue hemorrhagic fever Compli-cated dengue BLEEDING 

分 类 号：R512.8[医药卫生—内科学]