Imipenem/cilastatin-induced acute eosinophilic pneumonia:A case report  

作　　者：Gautam Jesrani Samiksha Gupta Amtoj Singh Lamba Shreya Arora Monica Gupta 

机构地区：[1]Department of General Medicine,Government Medical College and Hospital,Chandigarh,India

出　　处：《Journal of Acute Disease》2023年第6期250-253,共4页急性病杂志（英文版）

摘　　要：Rationale:Acute eosinophilic pneumonia(AEP)is an acute pulmonary illness caused by eosinophilic infiltration of the lung parenchyma.It can happen after using drugs such as daptomycin and minocycline.AEP induced by imipenem/cilastatin is a rare condition.Patient’s Concern:A 45-year-old male patient,who previously suffered from a urinary tract infection and treated with imipenem/cilastatin antibiotic,was presented to us with acute respiratory distress,soon after the initiation of the antibiotic.Computed tomography identified pulmonary infiltrates in the upper and middle lung fields and eosinophils were found to account for 36%of differential count of the broncho-alveolar lavage fluid.He also developed peripheral eosinophilia as the disease progressed.Diagnosis:AEP,secondary to imipenem/cilastatin therapy.Interventions:Steroid therapy was administered and imipenem/cilastatin antibiotic was discontinued.Outcomes:The patient improved completely following the therapy and had clear lung fields on follow-up.Lessons:Imipenem/cilastatin is an uncommon cause of AEP and requires close monitoring during therapy.

关 键 词：Acute eosinophilic pneumonia Broncho-alveolar lavage Imipenem/cilastatin Pulmonary infiltrate Peripheral eosinophilia 

分 类 号：R563.1[医药卫生—呼吸系统]