运用PCNE分类系统对呼吸道疾病患者进行药学监护的应用研究  

Application of PCNE classification system in pharmaceutical monitoring of patients with respiratory diseases

作　　者：康曼 张弦 李茗薇 张华[1] 徐静 王晓娟[1] KANG Man;ZHANG Xian;LI Mingwei;ZHANG Hua;XU Jing;WANG Xiaojuan(Department of Pharmacy,the First Affiliated Hospital of Anhui University of Science and Technology(Huainan First People’s Hospital),Huainan 232007,Anhui Province,China;Department of Obstetrics and Gynaecology,the First Affiliated Hospital of Anhui University of Science and Technology(Huainan First People’s Hospital),Huainan 232007,Anhui Province,China)

机构地区：[1]安徽理工大学第一附属医院(淮南市第一人民医院)药学部,安徽淮南232007 [2]安徽理工大学第一附属医院(淮南市第一人民医院)妇产科,安徽淮南232007

出　　处：《中国药师》2024年第2期336-344,共9页China Pharmacist

基　　金：安徽省高等学校科学研究项目(2022AH050803);淮南市指导性科技计划项目(2022159)。

摘　　要：目的 运用欧洲医药保健网(PCNE)分类系统对呼吸道疾病患者进行药学监护,探索呼吸科的有效药学监护模式,促进临床合理用药。方法 选取安徽理工大学第一附属医院2022年诊断为慢性阻塞性肺疾病(COPD)和肺部感染的住院患者,分为简单组和干预组;根据PCNE分类系统,对药物相关问题(DRPs)的类型、原因、干预、干预的接受情况及解决状态等方面进行分析。结果 共纳入病例120例,简单组60例,干预组60例。DRPs发生人数方面,简单组15例,干预组45例,两组差异有统计学意义(P <0.05)。DRPs共82个,主要涉及治疗效果(51.22%)和安全性(46.34%),原因为患者药物使用方法不正确、用法用量不适宜和未定期安全监测等。药师干预中,药物层面75个(91.46%),医生层面38个(46.34%),患者层面43个(52.44%);药师干预后,接受率为97.56%,74.39%的DRPs得到解决。结论 应用PCNE分类系统进行药学监护能够增强临床药师发现和处理DRPs的能力,减少临床发生不良事件的风险,促进患者的合理、安全用药;同时还有助于药学监护实施记录的标准化和规范化,可为呼吸科患者的药学服务模式提供参考。Objective To provide pharmaceutical monitoring using the Pharmaceutical Care Network Europe(PCNE) for patients with respiratory diseases,to explore effective pharmaceutical monitoring models in the department of respiratory,and to promote clinical rational drug use.Methods Inpatients diagnosed with chronic obstructive pulmonary disease(COPD) and lung infections in 2022 at the First Affiliated Hospital of Anhui University of Science and Technology were selected and divided into a simple group and an intervention group.According to the PCNE classification system,the types,causes,interventions,acceptance of interventions,and resolution status of drug-related problems(DRPs) were analyzed.Results A total of 120 cases were included,60 cases in the simple group and 60 cases in the intervention group.Regarding the number of DRPs,there were 15 cases in the simple group and 45 cases in the intervention group,and there was a significant difference between the two groups(P<0.05).There were a total of 82 DRPs,which were mainly related to therapeutic efficacy(51.22%) and safety(46.34%),and the reasons for this were that patients' incorrect medication usage method,inappropriate usage and dosage,and unscheduled safety monitoring,etc.The pharmacist interventions were 75(91.46%) at the drug level,38(46.34%) at the physician level,and 43(52.44%) at the patient level;a?ter the pharmacist interventions,the acceptance rate was in the range of 97.56%,and 74.39% of the DRPs were resolved.Conclusion PCNE classification system helps clinical pharmacists to enhance their ability to find and deal with DRPs,reduce the risk of clinical adverse events and promote reasonable and safe drug use.Meanwhile,it is conducive to the standardization of pharmaceutical care records for patients with respiratory diseases and provides reference for pharmaceutical service models for patients in the department of respiratory.

关 键 词：药物相关问题 欧洲医药保健网分类系统 药学监护 临床药师 

分 类 号：R969.3[医药卫生—药理学]