肢端肥大症合并妊娠一例并文献复习  

Acromegaly with pregnancy:A case report and review of literature

作　　者：鞠姜华 朱惠娟 王林杰 阳洪波 姚勇[3] 段炼 Ju Jianghua;Zhu Huijuan;Wang Linjie;Yang Hongbo;Yao Yong;Duan Lian(Key Laboratory of Endocrinology of National Health Commission,Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100730,China;Department of Endocrinology,Qilu Hospital(Qingdao),Cheeloo College of Medicine,Shandong University,Qingdao 266035,China;Department of Neurosurgery,Peking Union Medical College Hospital,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院内分泌科,国家卫生健康委员会内分泌重点实验室,100730 [2]山东大学齐鲁医院(青岛)内分泌科,266035 [3]中国医学科学院,北京协和医学院,北京协和医院神经外科,100730

出　　处：《中华内分泌代谢杂志》2024年第1期68-72,共5页Chinese Journal of Endocrinology and Metabolism

基　　金：中央高水平医院临床科研业务费资助项目(2022-PUMCH-A-155、2022-PUMCH-B-016)。

摘　　要：本文报道1例肢端肥大症患者妊娠期服用溴隐亭并成功分娩的诊治经过。回顾性总结了该患者2次妊娠前后的临床资料及治疗结局。该患者第2次妊娠期间口服溴隐亭,妊娠期病情较稳定,并足月剖宫产1女婴。本文提示肢端肥大症患者在病情稳定后妊娠可获得良好结局,妊娠期服用多巴胺受体激动剂没有增加围产期不良事件。This article reports the diagnosis and treatment of a case of acromegaly in a pregnant patient who took bromocriptine during pregnancy and delivered successfully.A retrospective summary of the clinical data and treatment outcomes before and after two pregnancies of the patient is provided.The patient took bromocriptine during the second pregnancy,and her condition remained stable.A baby girl was delivered by caesarean section at full term.The article suggests that pregnancy in acromegaly patients,after the stabilization of the condition,can lead to favorable outcomes.The use of dopamine receptor agonists during pregnancy does not increase adverse events during the perinatal period.

关 键 词：肢端肥大症 妊娠 多巴胺受体激动剂 安全性 

分 类 号：R714.2[医药卫生—妇产科学] R584.11[医药卫生—临床医学]