中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能研究进展  

Research Progress on Regulation of Coagulation Function in Children with Purpura Nephritis by Chinese Medicine Combined with Tripterygium Glycosides

作　　者：王已心 张君[2] WANG Yixin;ZHANG Jun(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《实用中医内科杂志》2024年第2期17-19,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家中医药行业专项研究项目(201507001-03)。

摘　　要：儿童紫癜性肾炎是儿童时期常见的继发性肾小球疾病,因其病情复杂、缠绵难愈、易于复发,往往存在预后不良的风险。此前临床上对紫癜性肾炎病因及发病机制仍存在争议,认为该病与凝血与纤溶功紊乱等因素相关,治疗上也多数采用药物联合治疗。文章就中药联合雷公藤多苷调节紫癜性肾炎患儿凝血功能相关研究、中西医治疗进展等方面进行综述,以期开拓预防和诊治的新思路。Henoch-Sch9nlein purpura nephritis(HSPN) is a secondary secondary glomerular disease in children,which is often associated with poor prognosis due to its complexity,intractability and ease of recurrence.Previously,the etiology and pathogenesis of HSPN were still controversial,and it was believed that the disease was related to factors such as coagulation and fibrinolytic mechanisms,most of the treatment used were drug combination therapy.This article reviewed the research related to the regulation of coagulation function in children with HSPN by traditional Chinese medicine combined with tripterygium glycosides as well as the treatment progress in traditional Chinese and Western medicine,with a view to developing new ideas for prevention and diagnosis and treatment.

关 键 词：紫癜性肾炎 雷公藤多苷 凝血机制 治疗 综述 

分 类 号：R272[医药卫生—中医儿科学]