2型糖尿病发生泌尿系结石的研究进展  

Research Progress of Urinary Calculi in Patients with Type Ⅱ Diabetes

作　　者：樊黎雪 韦景航 陈定江 王坚 梁泰生[2] 高宏君[2] FAN Lixue;WEI Jinghang;CHEN Dingjiang;WANG Jian;LIANG Taisheng;GAO Hongjun(Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China;Ruikang hospital urinary surgery affiliated to Guangxi University of Chinese,Nanning 530001,Guangxi,China)

机构地区：[1]广西中医药大学,广西南宁530001 [2]广西中医药大学附属瑞康医院,广西南宁530001

出　　处：《实用中医内科杂志》2024年第2期50-53,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：广西中西医结合肾脏疾病临床研究中心项目(桂科AD22035122)。

摘　　要：泌尿系结石的发病率在我国逐年上升,研究显示泌尿系结石与2型糖尿病之间存在联系,2型糖尿病患者泌尿系结石发生有其特殊之处,胰岛素抵抗、炎性反应、氧化应激等是联系两大疾病的纽带,在这些机制作用下尿液成分逐步发生变化,增加了2型糖尿病患者泌尿系结石的发生率,其所患结石类型以尿酸结石及草酸钙结石为主。2型糖尿病及泌尿系结石会共同作用于肾脏,使肾脏正常的内分泌功能和排泄代谢产物的作用受到影响。文章从2型糖尿病患者发生泌尿系结石的机制、对肾脏的损害及防治等方面进行阐述。the incidence rate of urinary calculi is increasing year by year in China.Research shows that there is a relationship between urinary calculi and type Ⅱ diabetes.The occurrence of urinary calculi in patients with type Ⅱ diabetes has its own characteristics.Insulin resistance,inflammatory reaction and oxidative stress are the links between the two diseases.Under the action of these mechanisms,the composition of urine gradually changes,increasing the incidence of urinary calculi in patients with type Ⅱ diabetes,The main type of stones are uric acid stones and calcium oxalate stones.Type Ⅱ diabetes and urinary calculi will act on the kidney together,affecting the normal endocrine function of the kidney and the excretion of metabolites.This article elaborates from the mechanism of urinary stones in patients with type Ⅱ diabetes and the damage and prevention of the kidneys.

关 键 词：2型糖尿病 泌尿系结石 代谢性疾病 糖尿病肾病 

分 类 号：R255.4[医药卫生—中医内科学]