狗脊化学成分、药理作用及质量控制的研究进展  

Research Progress on Chemical Constituents,Pharmacological Effects and Quality Control of Cibotii Rhizoma

作　　者：郭忠静 李恩念 赵志敏[1] 杨得坡[1] 徐新军[1] GUO Zhongjing;LI Ennian;ZHAO Zhimin;YANG Depo;XU Xinjun(College of Pharmacy,Sun Yat-sen University,Guangzhou 510006 Guangdong,China;Guangdong Yuansi South Pharmaceutical Biotechnology Co.,Ltd.,Pingyuan 514699 Guangdong,China)

机构地区：[1]中山大学药学院,广东广州510006 [2]广东远思南药生物科技有限公司,广东平远514699

出　　处：《中药新药与临床药理》2024年第1期152-157,共6页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家科技部重点研发计划项目“2022乡村产业共性关键技术研发与集成应用”(2022YFD1600300);南药产业技术体系创新团队建设项目(2021KJ142);南药产业技术体系创新团队建设项目(2022KJ142)。

摘　　要：狗脊具有悠久的民间及临床应用历史,常用于治疗腰膝酸软、手足麻木等症。其化学成分主要包括糖及糖苷类、芳香族类、挥发油类、蕨素类、黄酮类、甾体类、吡喃酮类、氨基酸类和无机元素。药理学研究表明,狗脊具有抗氧化、抗炎、抗骨质疏松、胃肠保护、抑菌、保肝、抗癌、镇痛等作用。该文系统综述了狗脊化学成分、药理活性及质量控制的研究现状,可为狗脊的深入开发和合理使用提供参考。Cibotii Rhizoma has a long history of folk usage and clinical applications,which is commonly used to treat symptoms such as waist and knee soreness,numbness of hands and feet.Its chemical components mainly include sugars and glycosides,aromatics,volatile oils,pterosins,flavonoids,steroids,pyranones,amino acids and inorganic elements.Pharmacological studies have shown that Cibotii Rhizoma has antioxidant,antiinflammatory,anti-osteoporosis,gastrointestinal protection,antibacterial,liver protection,anticancer,analgesic and other effects.This paper systematically reviews the research status of chemical constituents,pharmacological effects and quality control of Cibotii Rhizoma,which provides reference for the development and rational use of Cibotii Rhizoma.

关 键 词：狗脊 化学成分 药理作用 质量控制 

分 类 号：R284.1[医药卫生—中药学] R285.5[医药卫生—中医学]