慢性心力衰竭伴轻度认知障碍中医证素与认知功能的相关性研究  

Correlation Between TCM Syndrome Elements and Cognitive Function in Patients with Chronic Heart Failure

作　　者：骆睿翔 张晨[1] 庄锐 李星星 王禹萌 刘用 吴旸[3] 范宗静[3] LUO Ruixiang;ZHANG Chen;ZHUANG Rui;LI Xingxing;WANG Yumeng;LIU Yong;WU Yang;FAN Zongjing(Beijing University of Chinese Medicine,Beijing 100029,China;Beijing Emergency Medical Center,Beijing 100031,China;Dongfang Hospital of Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京急救中心,北京100031 [3]北京中医药大学东方医院,北京100078

出　　处：《世界中医药》2024年第2期225-229,共5页World Chinese Medicine

基　　金：国家自然科学基金面上项目(81573900);北中医新奥奖励基金项目(2019-XAJLJJ-019)。

摘　　要：目的:探讨慢性心力衰竭(CHF)患者中医证候要素与认知功能的相关性。方法:选取2021年5月至2022年3月北京中医药大学东方医院收治的94例CHF伴轻度认知功能障碍(MCI)患者作为研究对象,进行中医证候要素辨证,记录患者的一般资料,采用蒙特利尔认知评估量表(MoCA)对患者的认知功能进行评估,最后对中医证候要素与各项认知功能进行比较。结果:气虚证患者的视空间与执行能力评分更低,血瘀证患者的MoCA总分、注意与计算能力评分更低,痰浊证患者的MoCA总分、延迟回忆力以及抽象思维评分更低。结论:气虚证患者更容易出现视空间与执行能力的下降,血瘀证患者更容易出现注意与计算能力的下降,痰浊证患者更容易出现延迟回忆力和抽象思维能力的下降。Objective:To explore the correlation between TCM syndrome elements and cognitive function in patients with chronic heart failure(CHF).Methods:A total of 94 patients with CHF and mild cognitive impairment(MCI) admitted to Dongfang Hospital of Beijing University of Chinese Medicine from May 2021 to March 2022 were selected as subjects.The general information of the patients was recorded,and the cognitive function of the patients was evaluated by the montreal cognitive assessment(MoCA) scale.Finally,the TCM syndrome elements and each cognitive function were compared.Results:Patients with qi deficiency syndrome had lower visuospatial and executive ability scores,the patients with blood stasis syndrome had lower MoCA total scores,attention and calculation ability scores,and patients with phlegm turbidity syndrome had lower MoCA total scores,delayed recall and abstract thinking scores.Conclusion:Patients with qi deficiency syndrome are more likely to have a decline in visuospatial and executive ability,patients with blood stasis syndrome are more likely to have a decline in attention and calculation ability,and patients with phlegm turbidity syndrome are more likely to have a decline in delayed recall and abstract thinking ability.

关 键 词：慢性心力衰竭 认知功能障碍 痴呆 双心医学 量表 相关性 证候要素 中医 

分 类 号：R259[医药卫生—中西医结合]