角膜塑形镜矫正效果影响因素的数值模拟  

Numerical Simulation of Factors Influencing the Effectiveness of Orthokeratology Lens Correction

作　　者：胡郡琦 王晓君 张立华[3] 李晓娜 侯杰 HU Junqi;WANG Xiaojun;ZHANG Lihua;LI Xiaona;HOU Jie(College of Mechanical and Vehicle Engineering,Taiyuan University of Techndogy,Taiyuan 030024,China;College of Biomedical Engineering,Taiyuan University of Technology,Jinzhong 030600,China;Department of Excimer Laser,Shanxi Eye Hospital,Taiyuan 030002,China)

机构地区：[1]太原理工大学机械与运载工程学院,太原030024 [2]太原理工大学生物医学工程学院,山西晋中030600 [3]山西省眼科医院准分子激光科,太原030002

出　　处：《太原理工大学学报》2024年第2期376-383,共8页Journal of Taiyuan University of Technology

基　　金：国家自然科学基金资助项目(12072218,11872262);山西省自然科学基金资助项目(20210302123150)。

摘　　要：【目的】角膜形态以及角膜和塑形镜材料的力学性能对塑形镜矫正效果存在一定的影响。【方法】使用超弹性本构建立角膜配戴塑形镜的有限元模型,通过改变角膜的形态(不同曲率和厚度)以及角膜和塑形镜的材料参数,分析戴镜后角膜的生物力学响应。【结果】结果表明:角膜曲率变化4 m-1时,角膜中央区顶点处位移差值变化了15.7μm;角膜厚度变化75μm时,中央区顶点处位移差值变化了12.3μm;角膜材料参数k1值变化3倍时,角膜中央区顶点处位移差值的变化量为39.2μm,C10值变化4倍时位移差值的变化量为55.5μm,而塑形镜材料参数E值变化3倍时,位移差值的变化量仅为0.2μm.【结论】临床上采用角膜塑形镜矫正近视时,需要充分考虑角膜形态和角膜本身的力学性能对矫正效果的影响。【Purposes】The corneal shape and mechanical properties of cornea and contact lens ma⁃terial have a certain impact on the correction effect of contact lens.【Methods】In this paper,a finite el⁃ement model of corneal wearing orthokeratology lens was established by using hyperelasticity materi⁃als,and the biomechanical response of cornea after wearing lens was analyzed by changing the shape of cornea(different curvature and thickness)and the material parameters of cornea and orthokeratolo⁃gy lens.【Findings】The results showed that when the corneal curvature changed 4 m−1,the displace⁃ment difference at apex of the cornea central area changed by 15.7μm,and when the corneal thickness changed by 75μm,the displacement difference at apex of the central area changed by 12.3μm;when the corneal material parameter k1 increased by 3 times,the change of displacement difference at apex of the cornea central area was 39.2μm,when the C10 value increased by 4 times,the change of dis⁃placement difference was 55.5μm,while when the orthokeratology lens material parameter E in⁃creased by 3 times,the change of displacement difference was only 0.2μm.【Conclusions】When us⁃ing orthokeratology lens to correct myopia,it is necessary to fully consider the influence of corneal morphology and the mechanical properties of the cornea on the correction effect.

关 键 词：角膜 角膜塑形镜 有限元模拟 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]