柴胡疏肝汤加减联合甲硫咪唑治疗甲状腺功能亢进临床观察  

作　　者：伍梦依 

机构地区：[1]江西省九江市第一人民医院健康管理中心,江西九江332001

出　　处：《实用中医药杂志》2024年第2期240-242,共3页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察柴胡疏肝汤加减联合甲硫咪唑治疗甲状腺功能亢进的效果。方法:92例按随机数字表法分为两组各46例。两组均给予甲硫咪唑,观察组加用柴胡疏肝汤加减。结果:观察组总有效率高于对照组(P<0.05)。治疗后观察组胸胁满闷、失眠多梦、心烦易怒、恶心便溏评分与总甲状腺素(TT4)、游离甲状腺激素T3(FT3)、游离甲状腺激素T4(FT4)低于对照组,游促甲状腺素(TSH)高于对照组,两组比较差异均有统计学意义(P<0.05)。两组不良反应比较差异无统计学意义(P>0.05)。结论:柴胡疏肝汤加减联合甲硫咪唑治疗甲状腺功能亢进效果较好,且不良反应较少。Objective:To observe the effect of Chaihu Shugan decoction combined with methimazole in the treatment of hyperthyroidism.Methods:Nnety-two cases were randomly divided into two groups,46 cases in each group.Both groups were given methimazole,and the observation group were additionally given modified Chaihu Shugan Decoction in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the scores of chest fullness,insomnia,irritability,nausea and loose stool,total thyroxine(TT4),free thyroid hormone T3(FT3)and free thyroid hormone T4(FT4)in the observation group were lower than those in the control group,and thyroid stimulating hormone(TSH)was higher than that in the control group.The differences between the two groups were statistically significant(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:Chaihu Shugan Decoction combined with methimazole is effective in the treatment of hyperthyroidism,with fewer adverse reactions.

关 键 词：甲状腺功能亢进 柴胡疏肝汤 甲硫咪唑 对照治疗观察 

分 类 号：R582.1[医药卫生—内分泌]