Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction ofα-diazoesters,aryl isothiocyanates,amines and cyclic ethers  

作　　者：Yufen Lv Hongyu Ding Jinmao You Wei Wei Dong Yi 

机构地区：[1]Key Laboratory of Catalytic Conversion and Clean Energy in Universities of Shandong Province,School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165,China [2]College of Chemistry and Chemical Engineering,Shaoxing University,Shaoxing 312000,China [3]School of Pharmacy,Southwest Medical University,Luzhou 646000,China

出　　处：《Chinese Chemical Letters》2024年第2期415-419,共5页中国化学快报（英文版）

基　　金：financially supported by Natural Science Foundation of Shandong Province(No.ZR2021MB065);the major innovation fund of Shandong Province(No.2021ZDSYS_(2)3);the National Natural Science Foundation of China(Nos.21976105,22101237).

摘　　要：An additive-free and environmentally friendly strategy has been realized for the construction of S-substituted isothioureas through visible-light-induced multicomponent reaction starting fromα-diazoesters,aryl isothiocyanates,amines and cyclic ethers.This methodology features simple operation,mild reaction conditions,favorable functional group tolerance,easily available starting materials and high efficiency.

关 键 词：Visible-light Additive-free Four-component reaction S-Substituted isothioureas 

分 类 号：O623.8[理学—有机化学] O644.1[理学—化学]