红金消结胶囊治疗乳腺增生症临床观察  

Hongjin Xiaojie Capsule in Treating Hyperplasia of Mammary Glands

作　　者：张明 李湘奇 王莹 ZHANG Ming;LI Xiangqi;WANG Ying(Department of Traditional Chinese Medicine,The Second Affiliated Hospital of Shandong First Medical University,Shandong Province,Taian 271000,China;Breast Disease Diagnosis and Treatment Center,The Second Affiliated Hospital of Shandong First Medical University,Shandong Province,Taian 271000,China;Department of Rehabilitation Medicine,The Second Affiliated Hospital of Shandong First Medical University,Shandong Province,Taian 271000,China)

机构地区：[1]山东第一医科大学第二附属医院中医科,山东泰安271000 [2]山东第一医科大学第二附属医院乳腺疾病诊疗中心,山东泰安271000 [3]山东第一医科大学第二附属医院康复医学科,山东泰安271000

出　　处：《光明中医》2024年第6期1049-1052,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：山东省自然科学基金(No.ZR2020MH357);泰山市科技创新发展项目(No.2020NS092);山东省中医药科技发展计划(No.2021Z045)。

摘　　要：目的评价红金消结胶囊对乳腺增生症临床疗效及安全性。方法选取乳腺增生症患者300例,分为观察组、对照组各150例(包含肝郁气滞型、痰瘀互结型和冲任失调型);对照组用红金消结胶囊治疗,观察组用红金消结胶囊联合托瑞米芬治疗,2组均治疗12周,评价疗效。结果观察组有效率优于对照组(P<0.05);肝郁气滞型和痰瘀互结型疗效差异无统计学意义(P>0.05),冲任失调型观察组疗效优于对照组(P<0.05);观察组复发率低于对照组,不良反应发生率高于对照组(均P<0.05)。结论红金消结胶囊对乳腺增生症疗效较好,安全性高,但对冲任失调型乳腺增生症须联合托瑞米芬,才能达到更好的效果。Objective To evaluate the therapeutic effect and safety of Hongjin Xiaojie capsule on hyperplasia of mammary glands.Methods A total of 300 cases of hyperplasia of mammary glands were divided into observation group and control group,with 150 cases in each group(including liver-qi stagnation type,intermingled phlegm and blood stasis type and disharmony of Chong and conception channels type).The control group was treated with Hongjin Xiaojie capsule,and the observation group was treated with Hongjin Xiaojie capsule combined with toramiphene.Both groups were treated for 12 weeks,and the efficacy was evaluated.Results The effective rate of observation group was better than that of control group(P<0.05).There was no significant difference in the curative effect between liver-qi stagnation type and intermingled phlegm and blood stasis type(P>0.05).The curative effect of disharmony of Chong and conception channels type was better than that of control group(P<0.05).The recurrence rate of observation group was lower than that of control group,and the incidence of adverse reactions was higher than that of control group(P<0.05).Conclusion Hongjin Xiaojie capsule has good curative effect and high safety on hyperplasia of mammary glands,However,it must be combined with toramiphene to achieve better effect on the disharmony of Chong and conception channels type.

关 键 词：乳癖 乳腺增生症 红金消结胶囊 中成药疗法 

分 类 号：R269[医药卫生—中西医结合]