急诊外科中静脉快速滴注高渗盐液对脑外伤并休克患者预后的影响  

Effect of rapid intravenous infusion of hypertonic salt solution on prognosis of patients with brain trauma and shock in emergency surgery department

作　　者：张昆阳 陈涛 王晓蒙 ZHANG Kunyang;CHEN Tao;WANG Xiaomeng(Emergency Surgery Department,Ninth People's Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第九人民医院急诊外科,河南郑州450000

出　　处：《临床医学研究与实践》2024年第9期77-80,共4页Clinical Research and Practice

摘　　要：目的探讨急诊外科中静脉快速滴注高渗盐液对脑外伤并休克患者预后的影响。方法选取2020年10月至2023年10月我院急诊外科收治的84例脑外伤并休克患者为研究对象,以随机数字表法将其分为观察组(n=42,静脉快速滴注高渗盐液)和对照组(n=42,甘露醇+碳酸氢钠注射液)。比较两组的生命体征、格拉斯哥昏迷评分(GCS)、美国国立卫生研究院卒中量表(NIHSS)、简易智力状态检查量表(MMSE)评分及临床疗效。结果治疗30 min后、治疗2 h后,观察组的呼吸频率、心率(HR)、尿量优于对照组(P<0.05)。治疗1周后,观察组的GCS、MMSE评分高于对照组,NIHSS评分低于对照组(P<0.05)。观察组的治疗总有效率高于对照组(P<0.05)。结论静脉快速滴注高渗盐液能有效促进脑外伤并休克患者的生命体征改善和神经功能恢复。Objective To investigate the effect of rapid intravenous infusion of hypertonic salt solution on prognosis of patients with brain trauma and shock in emergency surgery department.Methods A total of 84 patients with brain trauma and shock admitted in the emergency surgery department of our hospital from October 2020 to October 2023 were selected as the study objects and divided into observation group(n=42,rapid intravenous infusion of hypertonic salt solution)and control group(n=42,mannitol+sodium bicarbonate injection)by random number table method.The vital signs,Glasgow Coma Score(GCS),National Institute of Health Stroke Scale(NIHSS),Mini-Mental State Examination(MMSE)scores and clinical efficacy were compared between the two groups.Results After 30 min and 2 h of treatment,the respiratory rate,heart rate(HR)and urine volume of the observation group were better than those of the control group(P<0.05).After 1 week of treatment,the GCS and MMSE scores in the observation group were higher than those in the control group,the NIHSS score was lower than that in the control group(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).Conclusion Rapid intravenous infusion of hypertonic salt solution can effectively improve vital signs and restore nerve function in patients with brain trauma and shock.

关 键 词：脑外伤 休克 静脉快速滴注 高渗盐液 

分 类 号：R338.63[医药卫生—人体生理学]