宁夏15家二级及以上医疗机构中药饮片处方用量分析  

Prescription Dose of Traditional Chinese Medicine Decoction Pieces in 15 Secondary and Above Medical Institutions in Ningxia

作　　者：田杰 王俊卿 纳金玲 黄丽 王艳平 TIAN Jie;WANG Junqing;NA Jinling;HUANG Li;WANG Yanping(Ningxia Hui Autonomous Region Hospital of Traditional Chinese Medicine and Institute of Traditional Chinese Medicine,Yinchuan,Ningxia,China 750021)

机构地区：[1]宁夏回族自治区中医医院暨中医研究院,宁夏银川750021

出　　处：《中国药业》2024年第6期32-35,共4页China Pharmaceuticals

基　　金：宁夏医科大学科学研究基金资助项目[XZ2019009]。

摘　　要：目的促进宁夏医疗机构对中药饮片的合理使用。方法按随机简单抽样原则,通过医院信息系统抽取宁夏回族自治区不同区域15家二级及以上医疗机构门诊2019年中医处方3032张。处方均由各医疗机构具有相关资质的中级及以上职称医师开具。统计各中药饮片使用频率、用量及与2020年版《中国药典(一部)》(简称药典)规定的相符情况。结果共涉及中药615味,平均每剂处方15~19味。非药食同源及药食同源中药饮片的临床常用量分别集中在4~10 g、11~15 g、16~20 g和0~10 g、11~20 g、21~30 g;使用频次排名前3的分别为川芎(765次、25.23%),北柴胡(734次、24.21%),麸炒白术(723次、23.85%)和茯苓(1275次、42.05%),当归(972次、32.06%),甘草片(923次、30.44%)。使用频次排名前30的非药食同源及药食同源中药饮片临床常用量与药典相符率分别为60.03%和70.35%;15家医疗机构有毒、小毒中药饮片用量与药典相符率分别为44.61%和45.60%。结论宁夏二级及以上医疗机构中药饮片处方使用总体较规范。为确保药典的权威性和科学性,建议药典进行再版时,加大中药饮片临床用药剂量与临床疗效的研究力度,修正部分药物的用量范围,区分药食同源和非药食同源中药饮片,以更符合临床实际,保证用药安全。Objective To promote the rational use of traditional Chinese medicine(TCM)decoction pieces in medical institutions in Ningxia.Methods A total of 3032 TCM prescriptions in the outpatient service of 15 secondary and above medical institutions in different regions of Ningxia Hui Autonomous Region in 2019 were selected from the hospital information system based on the random simple sampling method.The above prescriptions were all prescribed by the physicians with middle or high professional titles who were qualified to prescribe TCM prescriptions in various medical institutions.The use frequency,dose of various TCM decoction pieces and their accordance rate with the regulations of the Chinese Pharmacopoeia(2020 Edition,VolumeⅠ,referred to as the Pharmacopoeia)were analyzed.Results A total of 615 TCMs were involved,with an average of 15-19 TCMs per dose.The clinical commonly use doses of TCM decoction pieces without the homology of medicine and food were mainly in the range of 4-10 g,11-15 g,16-20 g,while those of TCM decoction pieces with the homology of medicine and food were mainly in the range of 0-10 g,11-20 g,21-30 g.The top three commonly used TCM decoction pieces without the homology of medicine and food were Chuanxiong Rhizoma(765 times,25.23%),Bupleurum chinense(734 times,24.21%),stir-baked Atractylodis Macrocephalae Rhizoma in bran(723 times,23.85%)respectively,and the top three TCM decoction pieces with the homology of medicine and food were Poria(1275 times,42.05%),Angelicae Sinensis Radix(972 times,32.06%),Liquorice Tablets(923 times,30.44%)respectively.The accordance rates of the clinical commonly use doses of the top 30 commonly used TCM decoction pieces without and with the homology of medicine and food with the regulations of the Pharmacopoeia were 60.03%and 70.35%respectively.The accordance rates of use doses of toxic and low-toxic TCM decoction pieces in 15 medical institutions with the regulations of the Pharmacopoeia were 44.61%and 45.60%respectively.Conclusion The prescription application of T

关 键 词：中药饮片 《中国药典》 超剂量 药食同源 非药食同源 量-效关系 

分 类 号：R95[医药卫生—药学]