SPECT/CT融合骨显像评估异位骨化的成熟度  

The evaluation of maturity of heterotopic ossification by SPECT/CT fusion bone imaging

作　　者：李培岭 赵振江 刘玉珂 魏娟 郭智萍 LI Peiling;ZHAO Zhenjiang;LIU Yuke;WEI Juan;GUO Zhiping(Department of Radiology,Luoyang Orthopedic-Traumatological Hospital of He’nan Province(He’nan Provincial Orthopedic Hospital),Zhengzhou 450000,China;He’nan Key Laboratory of Chronic Disease Management,Zhengzhou 450000,China)

机构地区：[1]河南省洛阳正骨医院(河南省骨科医院)放射科,河南郑州450000 [2]河南省慢病健康管理重点实验室,河南郑州450000

出　　处：《实用放射学杂志》2024年第2期270-274,共5页Journal of Practical Radiology

基　　金：河南省科技攻关计划项目(202102310362)。

摘　　要：目的探讨单光子发射计算机断层成像(SPECT)/CT融合骨显像评估异位骨化(HO)的成熟度和代谢状态。方法回顾性分析57例经病理或随访证实为HO患者的临床和SPECT/CT融合骨显像资料,依据CT对HO进行分期,分析HO的放射性浓聚特征。结果57例中52例单发,5例多发,共63个病灶,多位于髋关节(55.6%、35/63)和大腿(19.0%、12/63)。CT分期中期41个,晚期22个;SPECT/CT融合骨显像视觉评估,中期病灶多呈团状或片状、中度或高度放射性浓聚(75.6%、31/41),浓聚范围多等于或大于CT显示全部或局限骨化范围(21/41、50.1%),浓聚高的部位主要位于骨化密度混杂区域;晚期病灶多无放射性浓聚(72.7%、16/22)。结论SPECT/CT融合骨显像可显示HO放射性浓聚的范围、程度及评估成熟度,并能对具有成骨细胞活性的区域进行准确定位,为手术时机的选择提供科学的依据。Objective To evaluate the maturity and metabolic status of heterotopic ossification(HO)by single-photon emission computed tomography(SPECT)/CT fusion bone imaging.Methods The clinical and SPECT/CT fusion bone imaging data of 57 patients with HO confirmed by pathology or follow-up were analyzed retrospectively.HO was graded by CT,and the characteristics of radioactive concentration of HO were analyzed.Results Of 57 cases,single lesion in 52 cases,and multiple lesions in 5 cases,with a total of 63 lesions,mostly located in the hip joint(55.6%,35/63)and thigh(19.0%,12/63).There were 41 lesions in the middle stage and 22 lesions in the late stage.In the visual evaluation of SPECT/CT fusion bone imaging,the middle stage lesions were mostly clumps or flakes,with moderate or high radioactive concentration(75.6%,31/41),furthermore,the concentration range was larger than or equal to the total or limited range of CT ossification(21/41,50.1%),with high concentration mainly located in the mixed areas of ossification density.The concentration of the late stage lesions was mostly non-radioactive(72.7%,16/22).Conclusion SPECT/CT fusion bone imaging can show the range,degree and maturity of HO radioactive concentration,and can accurately locate the area with osteoblastic activity,which provides scientific basis for the selection of surgical timing.

关 键 词：异位骨化 放射性核素显像 单光子发射计算机断层成像 计算机体层成像 

分 类 号：R681[医药卫生—骨科学] R445.6[医药卫生—外科学] R814.42[医药卫生—临床医学]