基于数据挖掘对中药治疗头风病的用药规律分析  

Study on Medication Rule of Traditional Chinese Medicine in Treatment of Head Wind Disease Based on Data Mining

作　　者：武玉洁 滑振 李运伦[1,2] WU Yujie;HUA Zhen;LI Yunlun(Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China)

机构地区：[1]山东中医药大学,山东济南250014 [2]山东中医药大学附属医院,山东济南250014

出　　处：《辽宁中医杂志》2024年第1期156-160,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(82104796);山东省自然科学基金项目(ZR2021QH219);辽宁中医药大学中医脏象理论及应用国家教育部重点实验室(zyzx110);国家中医药管理局项目(GZY-FJS-2020-216)。

摘　　要：目的通过数据挖掘发现中药治疗头风病的用药特点并分析总结其规律,为头风病的治疗提供理论依据及用药参考。方法通过检索式检索知网等数据库中自建库至2022年3月有关于中医药治疗头风病的临床医案并提取相关处方建立Excel数据库,使用IBM SPSS Modeler 18对提取的中药做频数分析、关联规则分析及聚类分析。结果合格文献67篇,共统计处方99个,含87味中药,共使用1276次。川芎的使用率最高为84.85%,其他居于前5位的分别是白芍、甘草、当归、白芷,辛、苦,温为首要性味,归经首归肝经,解表类药物的利用度最高,其次是补虚类及活血化瘀类药物,关联程度较高的主要药对为当归—甘草—川芎、当归—白芷—川芎、柴胡—甘草—川芎、僵蚕—川芎、柴胡—白芷—川芎等。结论中医药治疗头风病,多以活血化瘀、益气养血、平肝熄风为主,主要药物包括川芎、白芍、甘草、当归、白芷、柴胡等。Objective To find out the characteristics of TCM in the treatment of head wind disease and analyze and summarize its rules based on data mining and provide theoretical basis and medication reference for the treatment of head wind disease.Methods The clinical cases of TCM treatment of cephalopathy from self-built databases such as CNKI were searched by retrieval method and relevant prescriptions were extracted to establish Excel database.IBM SPSS Modeler 18 was used for frequency analysis and association rule analysis and cluster analysis of extracted TCM.Results There were 67 qualified literatures,including 99 statistical prescriptions,including 87 kinds of TCM and 1276 times of use.The utilization rate of Chuanxiong(Chuanxiong Rhizoma)was the highest at 84.85%,and the other top 5 were Baishao(Paeoniae Radix Alba),Gancao(Glycyrrhizae Radix Et Rhizoma),Danggui(Angelicae Sinensis Radix),Baizhi(Angelicae Dahuricae Radix)and Chaihu(Bupleuri Radix).Pungent,bitter and warm tastes are the main tastes,and the meridian tropism is mainly the liver meridian.The utilization rate of relieving the exterior drugs was the highest,followed by the drugs for tonifying deficiency and promoting blood circulation and removing blood stasis.The main drug pairs with high correlation degree were Danggui(Angelicae Sinensis Radix)-Gancao(Glycyrrhizae Radix Et Rhizoma)-Chuanxiong(Chuanxiong Rhizoma),Danggui(Angelicae Sinensis Radix)-Baizhi(Angelicae Dahuricae Radix)-Chuanxiong(Chuanxiong Rhizoma),Chaihu(Bupleuri Radix)-Gancao(Glycyrrhizae Radix Et Rhizoma)-Chuanxiong(Chuanxiong Rhizoma),Jiangcan(Bombyx Batryticatus)-Chuanxiong(Chuanxiong Rhizoma),Chaihu(Bupleuri Radix)-Baizhi(Angelicae Dahuricae Radix)-Chuanxiong(Chuanxiong Rhizoma),etc.Conclusion Traditional Chinese medicine mainly treats head wind disease by the drugs for promoting blood circulation and removing blood stasis,invigorating Qi and nourishing blood,calming liver and dispelling wind.The main drugs include Chuanxiong(Chuanxiong Rhizoma),Baishao(Paeoniae Radix Alba),Gancao(Glycyr

关 键 词：头风病 中药 用药规律 关联规则 聚类分析 

分 类 号：R285[医药卫生—中药学]