针灸联合内养功对慢性盆腔炎患者盆腔包块直径和子宫动脉血流动力参数的影响  

Observation on Effects of Acupuncture and Moxibustion Combined with Intrinsic-nourishing Exercise in the Treatment of Chronic Pelvic Inflammatory Disease on the Diameter of Pelvic Mass and Uterine Artery Hemodynamic Parameters in Patients

作　　者：杨春香 邸志芳 刘新 肖远德 YANG Chunxiang;DI Zhifang;LIU Xin;XIAO Yuande(Department of Rehabilitation,Hebei Rehabilitation Hospital,Qinhuangdao 066000,Hebei,China)

机构地区：[1]河北省康复医院,河北秦皇岛066000

出　　处：《辽宁中医杂志》2024年第1期183-187,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81774111);中医重点专科培育项目:上海市进一步加快中医药事业发展三年行动计划(2018—2020年)-中医心病专科。

摘　　要：目的针灸联合内养功治疗慢性盆腔炎对患者盆腔包块直径和子宫动脉血流动力参数的影响。方法将86例慢性盆腔炎患者以1∶1比例随机分为对照组和观察组各43例,对照组予以常规西医基础治疗,观察组在对照组的西医用药基础上加予针灸联合内养功治疗,评估两组治疗1个月经周期后的临床疗效,对比两组治疗前及治疗1个月经周期后的中医症状评分、最大肿块直径、疼痛程度[视觉模拟评分法(VAS)]、子宫动脉血流动力参数[子宫动脉血管搏动指数(PI)和血管阻力指数(RI)、收缩期峰流速度(Vs)]及血清炎症指标[补体C_(3)、单核细胞趋化蛋白-1(MCP-1)及转化生长因子-TGF-β1(TGF-β1)]水平。结果观察组的的临床总有效率显著高于对照组(88.37%vs 69.77%,P<0.05);治疗后,两组关于腹部疼痛、腰部疼痛、白带色黄共3项中医症状评分相比治疗前均有显著性下降(P<0.05),两组的最大肿块直径和VAS评分相比治疗前均显著降低(P<0.05),两组的PI、RI及Vs值均较治疗前有显著性增加(P<0.05),两组的血清补体C_(3)、MCP-1水平较治疗前有显著性降低(P<0.05),血清TGF-β1水平较治疗前有显著性提升(P<0.05),以上指标观察组的变化幅度显著大于对照组(P<0.05);两组不良反应总发生率无显著性差异(P>0.05);观察组疾病复发率显著低于对照组(4.65%vs 18.60%,P<0.05)。结论针灸联合内养功治疗慢性盆腔炎的疗效显著,能明显改善中医相关症状,缩小盆腔包块直径,并减少腰腹痛感,改善子宫动脉血流动力参数,并能纠正机体血清炎症反应,不良反应少,复发率低。Objective To observe the effect of Huoxue Qianyang Qutan Recipe(活血潜阳祛痰方,HQQR)on myocardial hypertrophy and myocardial mitochondrial function in obese hypertensive rats.Methods Eighty-six patients with chronic pelvic inflammatory disease were randomly divided into control group(43 cases)and observation group(43 cases)in a ratio of 1∶1.The control group was given conventional western medicine basic treatment while the observation group was additionally givenacupuncture and moxibustion combined with intrinsic-nourishing exercise on the basis of western medicine in the control group.The clinical efficacy after 1 menstrual cycle of treatment was evaluated,and the TCM symptoms scores,maximum mass diameter,pain degree[visual analogue scale(VAS)],and uterine artery hemodynamic parameters[uterine artery pulsatility index(PI),vascular resistance index(RI),peak systolic flow velocity(Vs)]and serum inflammatory indicators[complement C_(3),monocyte chemoattractant protein-1(MCP-1),transforming growth factor-TGF-β1(TGF-β1)]were compared between the two groups before treatment and after 1 menstrual cycle of treatment.Results The clinical total effective rate of observation group was significantly higher than that of control group(88.37%vs 69.77%,P<0.05).After treatment,the scores of three TCM symptoms such as abdominal pain,waist painand leucorrhea with yellow color in the two groups were significantly decreased compared with those before treatment(P<0.05),and the maximum mass diameter and VAS score of both groups were significantly reduced(P<0.05)while the PI,RI and Vs were significantly enhanced(P<0.05),and the levels of serum complement C_(3) and MCP-1of the two groups were significantly lower than those before treatment(P<0.05)while the level of serum TGF-β1 was significantly higher than that before treatment(P<0.05),and the changes of the above indicators in observation group were significantly greater than those in control group(P<0.05).There was no significant difference in the total incidence rate of

关 键 词：慢性盆腔炎 针灸 内养功 盆腔包块直径 子宫动脉血流动力参数 

分 类 号：R271[医药卫生—中医妇科学]