二陈止嗽润肺方结合穴位敷贴治疗老年急性支气管炎效果观察  

Clinical Effect of Erchen Zhisou Runfei Formula(二陈止嗽润肺方) Combined with Acupoint Application in Treatment of Senile Acute Bronchitis

作　　者：乔亚珍[1] 钟新春[1] 刘超武[1] QIAO Yazhen;ZHONG Xinchun;LIU Chaowu(The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300000,China)

机构地区：[1]天津中医药大学第一附属医院,天津300000

出　　处：《辽宁中医杂志》2024年第2期119-122,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：天津市科技计划项目(18PTLCSY00440)。

摘　　要：目的评估二陈止嗽润肺方结合穴位敷贴治疗老年急性支气管炎临床效果。方法研究纳入94例老年急性支气管炎患者(2019年1月—2021年12月)进行研究,将纳入患者以随机数字表法分为常规治疗组与中医治疗组,各47例,常规治疗组患者采取西医常规治疗,中医治疗组患者在常规西医治疗基础上结合二陈止嗽润肺方及穴位敷贴治疗,各组数据观察:疗效、治疗前后中医证候(咳嗽气粗、口干口苦、痰多黄稠、烦躁不安等)积分变化、动脉血氧分压(PaO_(2))及动脉血二氧化碳分压(PaCO_(2))水平变化、用力肺活量(FVC)、第1秒用力呼气容积(FEV1)及最大呼气峰流速百分比(PEF%)指标变化、血清白细胞介素-4(IL-4)及白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平变化、不良反应。结果中医治疗组患者治疗总有效率(95.74%,45/47)高于常规治疗组(82.98%,39/47),P<0.05;治疗前,各组患者中医证候(咳嗽气粗、口干口苦、痰多黄稠、烦躁不安等)积分、PaO_(2)及PaCO_(2)、FVC、FEV1、PEF%、IL-4、IL-6、hs-CRP等指标均改善,中医治疗组患者中医证候(咳嗽气粗、口干口苦、痰多黄稠、烦躁不安等)积分、PaO_(2)及PaCO_(2)、FVC、FEV1、PEF%、IL-4、IL-6、hs-CRP等指标治疗后均优于常规治疗组,P<0.05;常规治疗组患者1例恶心,中医治疗组患者1例皮肤过敏,两组不良反应率均较低,P>0.05。结论二陈止嗽润肺方结合穴位敷贴治疗老年急性支气管炎临床效果显著,患者症状及肺功能改善,不良反应少,治疗安全可靠。Objective To evaluate the clinical effect of Erchen Zhisou Runfei Formula(二陈止嗽润肺方)combined with acupoint application in the treatment of elderly acute bronchitis.Methods A total of 94 elderly patients with acute bronchitis(January 2019 to December 2021)were included in this study.The patients were randomly divided into conventional treatment group and traditional Chinese medicine(TCM)treatment group,with 47 cases in each group.The patients in the TCM treatment group were treated with Erchen Zhisou Runfei Formula and acupoint application on the basis of conventional Western medicine treatment.The curative effect,the integral change of TCM symptoms(cough,rough breath,dry mouth,bitter mouth,yellow and thick phlegm,irritability,etc.),the values of arterial partial pressure of oxygen(PaO_(2))and arterial partial pressure of carbon dioxide(PaCO_(2))before and after treatment,forced vital capacity(FVC),forced expiratory volume in one second(FEV1)and percentage of maximum peak expiratory flow rate(PEF%),serum levels of interleukin-4(IL-4),interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP)and adverse reactions of the two groups were compared.Results The total effective rate of the TCM treatment group(95.74%,45/47)was higher than that of conventional treatment group(82.98%,39/47)(P<0.05).Before treatment,the scores of traditional Chinese medicine symptoms(cough,rough breath,dry mouth,bitter mouth,yellow and thick phlegm,irritability,etc.),the values of PaO_(2),PaCO_(2),FVC,FEV1 and PEF%,the levels of IL-4,IL-6,hs-CRP and other indicators were improved in two groups.After treatment,the scores of TCM symptoms(cough,rough breath,dry mouth,bitter mouth,yellow and thick phlegm,irritability,etc.),the values of PaO_(2),PaCO_(2),FVC,FEV1 and PEF%,the levels of IL-4,IL-6,hs-CRP and other indicators in the TCM treatment group were better than those in the conventional treatment group(P<0.05).There was 1 case of nausea in the conventional treatment group and 1 case of skin allergy in the TCM treatment group

关 键 词：老年急性支气管炎 二陈止嗽润肺方 穴位敷贴 疗效 不良反应 

分 类 号：R256.1[医药卫生—中医内科学]