川芎的化学成分和药理作用研究进展  

Research progress on chemical constituents and pharmacological effects of Chuanxiong Rhizoma

作　　者：梁旗 张来宾[1] 吕洁丽[1] LIANG Qi;ZHANG Laibin;LYU Jieli(School of Pharmacy,Xinxiang Medical University,Xinxiang 453003,Henan Province,China)

机构地区：[1]新乡医学院药学院,河南新乡453003

出　　处：《新乡医学院学报》2024年第3期275-285,共11页Journal of Xinxiang Medical University

基　　金：国家自然科学基金资助项目(编号:81773898);河南省优秀青年科学基金资助项目(编号:212300410066)。

摘　　要：川芎来源于伞形科植物川芎的干燥根茎,具有活血行气、祛风止痛的功效。川芎中主要含有苯酞、生物碱、酚酸、多糖等化学成分。药理研究表明,川芎对心脑血管系统、神经系统、呼吸系统等均具有一定的药理活性,主要表现为抗脑缺血、抗血栓、镇痛、抗炎、抗氧化、抗哮喘等药理作用。本文对川芎的化学成分及药理作用进行系统整理和归纳,以期为临床应用和资源开发提供参考。Chuanxiong Rhizoma,the dried rhizome of Ligusticum chuanxiong Hort.(Umbelliferae),has the effects of activating blood,promoting the circulation of Qi,dispelling pathogenic wind,and relieving pain.Chuanxiong Rhizoma contains phthalides,alkaloids,phenolic acids,and polysaccharides.Pharmacological research indicates that Chuanxiong Rhizoma has various pharmacological activities on the cardiovascular system,nervous system,and respiratory system,which are mainly manifested as anti-cerebral ischemia,anti-thrombosis,analgesia,anti-inflammation,antioxidation,and anti-asthma effects.In this paper,the chemical constituents and pharmacological effects of Chuanxiong Rhizoma are systematically summarized in order to provide references for its clinical application and resource development.

关 键 词：川芎 化学成分 药理作用 

分 类 号：R932[医药卫生—生药学]