针刺治疗功能性消化不良的神经影像学研究进展  

Neuroimaging research progress of acupuncture treatment for patients with functional dyspepsia

作　　者：何雨杞 张攀 毛杨科 李思扬 曾芳[1,2,3] 尹涛 HE Yu-qi;ZHANG Pan;MAO Yang-ke;LI Si-yang;ZENG Fang;YIN Tao(Acupuncture-moxibustion and Tuina School,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Acupuncture-moxibustion and Brain Science Research Center,Chengdu University of Traditional Chinese Medicine,Chengdu 61l137;Key Laboratory of Sichuan Province for Acupuncture-moxibustion and Chronobiology,Chengdu 610075)

机构地区：[1]成都中医药大学针灸推拿学院,成都610075 [2]成都中医药大学针灸脑科学研究中心,成都611137 [3]针灸与时间生物学四川省重点实验室,成都610075

出　　处：《针刺研究》2024年第2期192-197,共6页Acupuncture Research

基　　金：国家自然科学基金面上项目(No.81973960);国家自然科学基金青年项目(No.82205285);四川省科技厅青年科技创新研究团队项目(No.2019JDTD0011);四川省科技厅科技创新苗子工程重点项目(No.2020JDRC0105)。

摘　　要：神经影像技术为研究针刺效应机制提供了客观、可视化的研究手段。本文在系统检索既往基于神经影像技术的针刺治疗功能性消化不良临床研究的基础上,从穴位效应特异性、效应影响因素、不同机体应答特征、针刺疗效预测4个方面对既往研究内容进行归纳总结,提出针刺治疗功能性消化不良中枢整合具有疾病靶向性、循经特异性和动态条件性特征。最后,结合当前研究现状,从研究对象、影响因素、结果验证3个方面对未来研究提出展望,以期为今后深入开展相关研究提供参考。Neuroimaging technology provides objective and visualized research tool to study the mechanisms of acupuncture effects.Building on a systematic review of previous clinical studies on acupuncture treatment for functional dyspepsia using neuroimaging technology,this paper summarizes and synthesizes past researches from 4 aspects:acupoint-specific effects,factors influencing the effects,different physiological responses,and predictive factors for acupuncture efficacy.It suggests that acupuncture treatment for FD involves central integration with disease-targeted(acupuncture treatment can target and regulate abnormal brain functional activity patterns in patients with FD),meridian-specific(stimulation of specific acupuncture points along the stomach meridian can significantly regulate abnormal brain functional activity patterns in FD patients),and dynamic conditional features(the effects of acupuncture treatment for FD are influenced by multiple factors).Lastly,considering the current research status,this paper outlines prospects in terms of research subjects,influencing factors,and result validation,aiming to provide references for future in-depth research.

关 键 词：功能性消化不良 针刺 神经影像 功能磁共振成像 

分 类 号：R246.1[医药卫生—针灸推拿学]