2023年河南省某医院≤5岁肺炎球菌性疾病高风险儿童肺炎球菌疫苗接种率和影响因素调查  

Pneumococcal vaccine coverage and factors influencing coverage among≤5-year-old children at high risk for pneumococcal disease in a hospital in Henan province in 2023

作　　者：包黎明 姬艳芳[3] 甄兴刚 郑徽[1,2] 李明爽 张肖肖[3] 张延炀[3] 尹遵栋[1,2] Bao Liming;Ji Yanfang;Zhen Xinggang;Zheng Hui;Li Mingshuang;Zhang Xiaoxiao;Zhang Yanyang;YinZundong(National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing 102206,China;National Immunization Program,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Henan Provincial Center for Disease Control and Prevention,Zhengzhou 450000,Henan,China;Henan Children's Hospital,Zhengzhou 450018,Henan,China)

机构地区：[1]传染病溯源预警与智能决策全国重点实验室,中国疾病预防控制中心,北京102206 [2]中国疾病预防控制中心免疫规划中心,北京100050 [3]河南省疾病预防控制中心,河南郑州450000 [4]河南省儿童医院,河南郑州450018

出　　处：《中国疫苗和免疫》2024年第1期66-70,共5页Chinese Journal of Vaccines and Immunization

摘　　要：目的分析肺炎球菌性疾病(Pneumococcal disease,PD)高风险儿童肺炎球菌疫苗接种率和影响因素。方法采用便利抽样方法选择河南省某医院2023年9-10月就诊的≤5岁PD高风险儿童开展问卷调查,分析肺炎球菌疫苗接种率和影响因素。结果调查儿童至少1剂次肺炎球菌疫苗接种率为37.44%(82/219),13价肺炎球菌多糖结合疫苗全程接种率为12.79%(28/219),其中<2岁、2-5岁分别为3.41%(3/88)、19.08%(25/131)。多因素Logistic回归分析显示,非本地、非呼吸系统疾病、家长未关注/了解过自费疫苗的儿童至少1剂次肺炎球菌疫苗接种率低[OR(95%CI):0.52(0.29-0.96)、0.51(0.26-1.00)、0.34(0.16-0.76)],家庭人均收入高的儿童接种率高[OR(95%CI):2.47(1.28-4.77)]。结论PD高风险儿童肺炎球菌疫苗接种率偏低;需采取针对性措施提高PD高风险儿童肺炎球菌疫苗接种率。Objective To analyze coverage of pneumococcal vaccine and factors influencing coverage among children at high risk for pneumococcal disease(PD).Methods We used a convenience sampling method to select children≤5 years of age at high risk for PD who visited a hospital of Henan province in September-October 2023.We conducted a questionnaire-based survey to determine coverage of pneumococcal vaccine and factors influencing coverage.Results Coverage with at least 1 dose of pneumococcal vaccine was 37.44%(82/219).Full-series 13-valent pneumococcal polysaccharide conjugate vaccine coverage was 12.79%(28/219),and was 3.41%(3/88)among<2-year-olds and 19.08%(25/131)among 2-5-year-olds.Logistic regression analysis showed that coverage with at least 1 dose of pneumococcal vaccine was low among subjects who were non-local residents,who had non-respiratory illnesses,and whose parents did not know about self-paid vaccines[OR(95%CI):0.52(0.29-0.96),0.51(0.26-1.00),0.34(0.16-0.76)].Coverage was high among subjects with a high average family income[OR(95%CI):2.47(1.28-4.77)].Conclusions Pneumococcal vaccine coverage was low among children at high risk for PD.We should take relevant countermeasures to improve pneumococcal vaccination of children at high risk for PD.

关 键 词：肺炎球菌疫苗 预防接种 接种率 影响因素 肺炎球菌性疾病高风险儿童 

分 类 号：R186[医药卫生—流行病学]