使用医科达AGL标准流程对多台加速器验收的可行性研究  

Feasibility of acceptance of multiple accelerators using Elekta AGL standard procedures

作　　者：赵亮 李桂元 王晓红 陈辛元 门阔 戴建荣 田源 Zhao Liang;Li Guiyuan;Wan Xiaohong;Chen Xinyuan;Men Kuo;Dai Jianrong;Tian Yuan(Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College Langfang Branch,Langfang 065001,China;Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院廊坊院区放疗科,廊坊065001 [2]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021

出　　处：《中华放射肿瘤学杂志》2024年第3期244-249,共6页Chinese Journal of Radiation Oncology

摘　　要：目的验证使用医科达"快速验收流程"(AGL)标准流程验收多台加速器的可行性。方法通过PTW Beamscan三维水箱对3台加速器束流进行调试,使束流达到AGL标准。对达到AGL标准的3台加速器进行剂量验证。使用中国医学科学院肿瘤医院简单野测试例,比较MapCheck 3面剂量测量结果与同一加速器模型计算得到的面剂量。随机选取头颈、食管、乳腺、肺、直肠等部位肿瘤的10例临床患者影像,分别采用容积弧形调强放疗(VMAT)和调强放疗(IMRT)技术进行计划设计,比较ArcCheck测量剂量与同一加速器模型计算得到的计划剂量。使用单因素方差分析对二维剂量和三维剂量的验证通过率进行统计学分析。结果3台加速器6 MV X射线在水下10 cm处的百分深度剂量(PDD10)分别为67.45%、67.36%、67.47%,且3台加速器之间最大偏差为0.11%。6 MV非均整模式(FFF)X射线的PDD10分别为67.33%、67.20%、67.20%,且3台加速器之间最大偏差为0.13%。3台加速器X射线各能量30 cm×30 cm Profile主轴上所有要求的离散点剂量与标准数据偏差小于±1%。对MapCheck 3二维剂量矩阵验证结果进行绝对γ分析,在10%阈值2 mm/3%标准下,中国医学科学院肿瘤医院测试例平均通过率均在99%以上且差异无统计学意义(P>0.05)。对ArcCheck验证结果进行绝对γ分析,在10%阈值条件下,2 mm/3%的通过率均在95%以上,3台加速器不同能量不同治疗技术的平均通过率最大差异分别为0.28%(6 MV,VMAT)、0.19%(6 MV FFF,VMAT)、0.56%(6 MV,IMRT)和0.05%(6 MV FFF,IMRT),差异无统计学意义(P>0.05)。结论与传统的加速器验收流程相比,使用AGL标准流程验收加速器,每台加速器验收时间缩短4~6周,并保证了患者放疗计划可以在各加速器之间互换执行。Objective To verify the feasibility of using Elekta accelerated go live(AGL)standard process for the acceptance of multiple accelerators.Methods The beams of three accelerators were adjusted by PTW Beamscan three-dimensional water tank to reach the AGL standard.Dose verification was performed for three accelerators that met AGL standards.A simple field test example from Cancer Hospital Chinese Academy of Medical Sciences was used to compare the MapCheck 3 surface dose measurement results with the surface dose calculated by the same accelerator model.Images of 10 patients including head and neck,esophagus,breast,lung and rectum were randomly selected.volumetric-modulated arc therapy(VMAT)and intensity modulated radiation therapy(IMRT)treatment techniques were used for planning design,and the measured dose of ArcCheck was compared with the planned dose calculated by the same accelerator model.One-way ANOVA was used to statistically analyze the passing rates of two-dimensional and three-dimensional dose verification.Results The 6 MV X-ray percentage depth dose at 10 cm underwater(PDD10)of three accelerators was 67.45%,67.36%,67.47%,and the maximum deviation between the three accelerators was 0.11%.The 6 MV flattenting filter free(FFF)mode X-ray PDD10 was 67.33%,67.20%,67.20%,and the maximum deviation between the three accelerators was 0.13%.All required discrete point doses on each energy 30 cm×30 cm Profile spindle of the three accelerator X-rays deviated less than±1%from the standard data.Absoluteγanalysis was performed on the results of MapCheck 3 two-dimensional dose matrix validation.Under the 10%threshold of 2 mm/3%standard,the average passing rate of the test cases in Cancer Hospital Chinese Academy of Medical Sciences was above 99%,and the difference was not statistically significant(P>0.05).Absoluteγanalysis was performed on the ArcCheck verification results.Under the 10%threshold,the pass rate of 2 mm/3%was all above 95%,the maximum average passing rate of the three accelerators with different energy a

关 键 词：加速器验收 AGL标准流程 测试例 

分 类 号：R197.39[医药卫生—卫生事业管理]