穿山龙与雷公藤随证施量策略在桥本甲状腺炎治疗中的运用  

Application of Ningpo yam rhizome and Tripterygium wilfordi in the treatment of Hashimoto's thyroiditis based on the strategy of determining dosage according to syndromes

作　　者：唐珊珊 姬航宇[2] 安学冬 江林林 连凤梅[2] TANG Shanshan;JI Hangyu;AN Xuedong;JIANG Linlin;LIAN Fengmei(Changchun University of Chinese Medicine,Changchun 130117,China;Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]长春中医药大学,长春130117 [2]中国中医科学院广安门医院,北京100053

出　　处：《吉林中医药》2024年第3期300-302,共3页Jilin Journal of Chinese Medicine

基　　金：国家自然科学基金项目(81274000);国家重点基础研究发展计划(973计划)(2010CB530601)。

摘　　要：因药施量,可以称之为与药相关的量效关系,是随证施量的核心内容之一。通过仝小林院士治疗桥本甲状腺炎验案1则,阐述穿山龙与雷公藤随证施量策略在桥本甲状腺炎治疗中的应用:毒性药物经过配伍,去性存用,用药剂量可适当增大;根据患者服药后反应,紧盯“症靶”“标靶”,调整用量;根据疾病及其证候群变化确定其“剂量阈”与“治疗窗”,选用最佳剂量。Deciding dosage according to a certain drug can be referred to as the dose-effect relationship related to drugs,which constitutes one of the core contents of determining dosage based on syndromes.This article elaborates on the application of the strategy by presenting the examples of Ningpo yam rhizome and Tripterygium wilfordi in the treatment of Hashimoto's thyroiditis,based on a case by Academician Tong Xiaolin.The strategy can be generalized as the following three aspects:Toxic drugs can be used after compatibility,and their dosage can be appropriately increased.According to patients'reactions after taking medicine,closely monitor their symptom targets and biochemical indicator targets,and adjust drug dosages.Determine the"dosage threshold"and"treatment window"based on the changes in the disease and its syndrome group,and figure out the optimal dosage.

关 键 词：随证施量 穿山龙 雷公藤 桥本甲状腺炎 

分 类 号：R581.4[医药卫生—内分泌]