碘佛醇影响UC-3500及UF-4000尿液分析1例及其机制探讨  

Investigating the Impact of Ioversol on Urine Analysis Using UC-3500 andUF-4000:a Case Study and Mechanistic Exploration

作　　者：谭阳阳 蔡信坚 张晓煜 武珍珍 赖媛媛 齐军 TAN Yangyang;CAi Xinjian;ZHANG Xiaoyu;WU Zhenzhen;LAI Yuanyuan;QI Jun(National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital,Department of Clinical Laboratory,Chinese Academy of Medical Sciences and PekingUnion Medical College,Shenzhen 518116,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院深圳医院,广东深圳518116

出　　处：《标记免疫分析与临床》2023年第12期2152-2155,共4页Labeled Immunoassays and Clinical Medicine

基　　金：深圳市恶性肿瘤临床医学研究中心(编号:深科技创新[2021]287号)。

摘　　要：尿液分析作为常规检验的重要组成部分,对临床诊疗工作有着重要的意义。在工作中,常有很多因素会干扰到尿液分析,如含造影剂等,但国内外目前尚无文献阐明其中的影响机制。本文以本实验室遇到的1例造影剂(碘佛醇)影响尿液干化学和有形成份分析的案例,对其可能的机制进行探讨,以期提高临床、检验相关人员对尿液分析的了解和重视。Urinalysis plays a crucial role in routine laboratory investigations,serving as a vital tool in clinical diagnostics.However,urine analysis is often susceptible to various factors that could disrupt its accuracy,including the presence of contrast agents.Surprisingly,there is lack a comprehensive understanding of the underlying mechanisms behind these interferences in the current literatures,both nationally and internationally.In light of this,this article aims to investigate the potential mechanisms underlying the impact of ioversol,a contrast agent,on the chemical and morphological analysis of urine.By examining a case encountered in our laboratory,we endeavor to enhance the understanding and awareness of urine analysis among clinicians and laboratory personnel,underscoring its essential clinical relevance.

关 键 词：碘佛醇 造影剂 尿液分析 流式细胞术 

分 类 号：R446.12[医药卫生—诊断学]