水凝胶的制备及其在细胞治疗方面的应用进展  

Research progress in preparation and applications in cell therapy of hydrogels

作　　者：武超雄 张琳华 朱敦皖 Wu Chaoxiong;Zhang Linhua;Zhu Dunwan(Tianjin Key Laboratory of Biomedical Materials,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300192,China)

机构地区：[1]中国医学科学院、北京协和医学院生物医学工程研究所,天津市生物医学材料重点实验室,天津300192

出　　处：《国际生物医学工程杂志》2023年第6期489-493,共5页International Journal of Biomedical Engineering

基　　金：国家自然科学基金(82072059,82172090)。

摘　　要：水凝胶是一种亲水的三维网络结构,其吸水溶胀后质地柔软,具有良好的生物降解性和生物相容性,与生物体组织相似,因此在生物医学领域有着广泛的应用。根据交联机制的不同,分类介绍了物理水凝胶和化学水凝胶的制备方法,并对水凝胶在细胞治疗方面的应用进展进行综述。Hydrogels are hydrophilic three-dimensional networks that exhibit soft and flexible textures after absorbing water,making them biocompatible and biodegradable.Due to their similarity to biological tissues,hydrogels find extensive applications in the field of biomedical mechanism.In this paper,the preparation methods of physical hydrogels and chemical hydrogels are introduced according to the different cross-linking agents,and the application progress of hydrogels in cell therapy is reviewed.

关 键 词：水凝胶 生物降解性 生物相容性 细胞治疗 

分 类 号：TQ427.26[化学工程] R318.08[医药卫生—生物医学工程]