2020—2022年杭州出入境人员梅毒流行病学分析  

Epidemiological Analysis of Syphilis among Entry-exit Personnel at Hangzhou Port from 2020 to 2022

作　　者：鲍泽英 娄家怡 张小平 陈淑丹 BAO Ze-Ying;LOU Jia-Yi;ZHANG Xiao-Ping;CHEN Shu-Dan(Hangzhou International Travel Health Care Center(Hangzhou Customs Ports Outpatient Departments),Hangzhou 310012;Hangzhou Airport Customs,Hangzhou 310003)

机构地区：[1]杭州国际旅行卫生保健中心(杭州海关口岸门诊部),杭州310012 [2]杭州机场海关,杭州310003

出　　处：《中国口岸科学技术》2023年第12期56-60,共5页China Port Science and Technology

摘　　要：本文通过对杭州口岸出入境人群进行梅毒螺旋体感染的血清学检测和临床资料分析,全面了解梅毒在杭州口岸出入境人群中的感染和流行特点,为加强口岸传染病监测和预防控制工作提供基础数据。实验采用梅毒螺旋体明胶颗粒凝集试验(Treponema pallidiae particle agglutination test,TPPA)检测特异性抗体,并用甲苯胺红不加热血清试验(Toluidine red unheated serum test,TRUST)检测非特异性抗体进行评估。实验结果显示,杭州口岸2020—2022年共有出入境人员41483人,其中出境人员21076人次,入境人员20407人次,男女比例3∶2。该段时间梅毒特异性抗体(TPPA法)阳性147例,非特异性抗体(TRUST法)阳性50例,以20~60岁年龄段人群为主。检测梅毒感染阳性率为0.35%。2020—2022年杭州口岸梅毒抗体检测结果提示,梅毒在出入境人群中特别是劳务人群中依旧处于流行趋势,警示我们在加强对出入境人员的传染病筛查的同时,还需加强对全体民众进行健康宣传,有必要时干预高危行为,以控制梅毒螺旋体向健康人群传播扩散。Through the serological detection and clinical data analysis of treponema pallidiae infection among the entry-exit population at Hangzhou Port,the infection and epidemic characteristics of syphilis among the entry-exit population at Hangzhou Port were comprehensively analyzed,and the basic data was provided for strengthening the surveillance and prevention of infectious diseases at the port.Treponema pallidiae particle agglutination test(TPPA)was used to detect specific antibodies,and toluidine red unheated serum test(TRUST)was used to detect non-specific antibodies.The result shows Hangzhou Port has a total of 41,483 entryexit personnel from 2020 to 2022,including 21,076 outbound and 20,407 inbound,with a male to female ratio of 3:2.During this period,147 cases were positive for TPPA and 50 cases were positive for TRUST,mainly in the 20 to 60 age group.The positive rate of syphilis infection was 0.35%.The results of syphilis antibody surveillance at Hangzhou Port from 2020 to 2022 indicate that syphilis is still prevalent among entry-exit personnel,especially among labor workers,which warns us that while strengthening the infectious disease screening of entry-exit personnel,it is also urgent to promote health education of the entire population,and intervene high-risk behaviors if necessary,so as to control the spread of treponema pallidum to healthy people.

关 键 词：梅毒 出入境人群 传染病 监测 

分 类 号：R759.1[医药卫生—皮肤病学与性病学] R181.3[医药卫生—临床医学]