具有avarane骨架结构的Dysidea属海绵来源的倍半萜醌/氢醌类天然产物的合成研究进展  

Research Progress in the Synthesis of Sesquiterpene Quinones and Hydroquinones Natural Products with Avarane Skeleton from Dysidea sp.

作　　者：荀稳 蒋丽清 陈晓蕾 吴静纯 梁飞燕 邓懿楠 许波 Xun Wen;Jiang Liqing;Chen Xiaolei;Wu Jingchun;Liang Feiyan;Deng Yinan;Xu Bo(School of Food and Pharmaceutical Engineering,Zhaoqing University,Zhaoqing,Guangdong 526061;School of Chemical Biology and Biotechnology,Shenzhen Graduate School of Peking University,Shenzhen,Guangdong 518055)

机构地区：[1]肇庆学院食品与制药工程学院,广东肇庆526061 [2]北京大学深圳研究生院化学生物与生物技术学院,广东深圳518055

出　　处：《有机化学》2023年第12期4188-4212,共25页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.22101011,22201245);肇庆学院大学生创新创业训练计划(No.S202110580075)资助项目.

摘　　要：将具有avarane骨架结构的Dysidea属海绵来源的倍半萜醌/氢醌类天然产物按照连接醌/氢醌部分和倍半萜部分的键的差异分为三类,并以关键的合成策略为线索,分别对目前已报道的这三类倍半萜醌/氢醌类天然产物的合成方法进行了较为详细的阐述,期望能对其他天然产物的合成研究提供帮助.Sesquiterpene quinones and hydroquinones obtained from the marine sponge Dysidea sp.with avarane skeleton are classified into three categories based on the differences of the bond connecting the quinone/hydroquinone unit and the sesquiterpene unit.The reported synthetic methods for these three types of natural products are reviewed in detail based on their key synthetic strategies with the aim of assisting in the synthesis of other natural products.

关 键 词：倍半萜醌/氢醌 Dysidea属海绵 avarane骨架 合成策略 

分 类 号：O629[理学—有机化学]