Prevalence and influencing factors of cognitive frailty in elderly with diabetes mellitus in China:A meta-analysis  

作　　者：LIU Ting SONG Mi DIAO Zi-yan PI Hong-ying 

机构地区：[1]Medical School of Chinese PLA,Beijing 100853,China [2]Department of Gastroenterology,the Second Medical Center,Chinese PLA General Hospital,Beijing 100853,China [3]Air Force Hospital of Northern Theater Command,Shenyang 110042,China [4]Medical Service Training Center,Chinese PLA General Hospital,Beijing 100853,China

出　　处：《Journal of Hainan Medical University》2023年第22期53-61,共9页海南医学院学报（英文版）

基　　金：Military Medical Innovation Project (No.18CXZ034);National Key Research andDevelopment Program (No.2018YFC2001400,2020YFC2008601)。

摘　　要：Objective:To systematically review the epidemiological characteristics and influencing factors of cognitive frailty in Chinese elderly with diabetes mellitus.Methods:PubMed,Embase,Web of Science,CINAHL,Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang and Chinese biomedical literature database(CBM)were electronically searched to collect cross-sectional studies on the prevalence and influencing factors of cognitive frailty in Chinese elderly with diabetes mellitus from inception to November 1st,2022.After quality evaluation and data extraction of included studies,R4.2.2 software was used to perform metaanalysis.Results:A total of 7 Chinese and one English literatures involving 2208 participants were included.The results of meta-analysis showed that the prevalence rate of cognitive frailty in elderly diabetic patients was 17.1%(95%CI 8.7%to 30.9%).Subgroup analysis showed that the prevalence rate of cognitive frailty was 10.2%(95%CI 5.0%to 19.7%)in old diabetic adults in community,35.7%(95%CI 20.8%to 53.9%)in hospital,and the difference was statistically significant(P=0.01).The prevalence rate of cognitive frailty was 21.7%(95%CI 10.3%to 40.2%)in male diabetic old adults,24.2%(95%CI 13.3%to 40.1%)in female diabetic old adults,and the difference was not statistically significant(P=0.81).The rate was 12.6%(95%CI 6.6%to 22.5%)in 60~69 years old group,25.8%(95%CI 12.6%to 45.5%)in 70~79 years old group,53.0%(95%CI 23.9%to 80.2%)in diabetic old adults aged 80 years and above,and the difference was statistically significant(P=0.02).The influencing factors for cognitive frailty in diabetic old adults included educational level[OR=0.230,95%CI(0.117~0.454),P<0.0001],regular exercise[OR=0.357,95%CI(0.217~0.588),P<0.01],malnutrition[OR=2.372,95%CI(1.472~3.822),P=0.0004],depression[OR=3.207,95%CI(2.156~4.768),P<0.0001],and HbA1c≥7.0%[OR=3.112,95%CI(1.880~5.152),P<0.0001].Conclusion:The prevalence of cognitive frailty in Chinese elderly patients with diabetes is high,and there are differences in cognitive

关 键 词：Aged Diabetes mellitus Cognitive frailty META-ANALYSIS 

分 类 号：R587.2[医药卫生—内分泌] R749.1[医药卫生—内科学]