持续性躯体形式疼痛障碍的发病机制  

The pathogenesis of persistent somatoform pain disorder

作　　者：李卓伦 孙武平 熊东林 LI Zhuo-lun;SUN Wu-ping;XIONG Dong-lin(Department of Pain Medicine,Huazhong University of Science and Technology Union Shenzhen Hospital,Shenzhen Key Laboratory of Pain Medicine,Shenzhen 518052,China)

机构地区：[1]华中科技大学协和深圳医院疼痛科,深圳市疼痛学实验室,深圳518052

出　　处：《中国疼痛医学杂志》2024年第3期166-172,共7页Chinese Journal of Pain Medicine

基　　金：深圳市卫南山区技术研发和创意设计项目分项资金(NS2021014)。

摘　　要：持续性躯体形式疼痛障碍(persistent somatoform pain disorder, PSPD)是临床较常见且复杂的疾病,是“躯体形式障碍”的一个亚型,病人通常反复就诊、疗效不确定且伴高度焦虑。PSPD的发病机制目前尚不明确,暂无特效药物,临床治疗多以抗抑郁药、抗精神病药等药物治疗为主,并联合心理疗法。本文回顾总结近年来PSPD在神经生理机制方面的研究进展,以期为明确PSPD的发病机制提供参考。Persistent somatoform pain disorder(PSPD)is a common and complex clinical disease and a subtype of the somatoform disorder.Patients usually have repeated visits,uncertain treatment outcomes,and high level of anxiety.The pathogenesis of PSPD is currently unclear,and there are no specific drugs available.Clinical treatment is mostly based on antidepressant drugs,antipsychotic drugs and other drug treatment,combined with psychotherapy.In this paper,we review and summarize the recent research progress of PSPD in neurophysiological mechanisms,in order to provide reference for clarifying the pathogenesis of PSPD.

关 键 词：持续性躯体形式疼痛障碍 疼痛 机制 

分 类 号：R402[医药卫生—临床医学]