基于科研范式变革的实验动物资源创新发展  

Reflection on the Innovation and Development of Laboratory Animal Resources Based on the Transformation of Scientific Research Paradigm

作　　者：贺争鸣[1] 陈洪岩[2] 陈振文[3] 孙岩松 巩薇[1] 梁春南[1] HE Zhengming;CHEN Hongyan;CHEN Zhenwen;SUN Yansong;GONG Wei;LIANG Chunnan(National Institutes for Food and Drug Control,Beijing 102629,China;Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150069,China;Capital Medical University,Beijing 100069,China;Academy of Military Medical Sciences,Beijing 100039,China)

机构地区：[1]中国食品药品检定研究院,北京102629 [2]中国农业科学院哈尔滨兽医研究所,哈尔滨150069 [3]首都医科大学,北京100069 [4]军事医学研究院,北京100039

出　　处：《实验动物科学》2024年第1期84-88,共5页Laboratory Animal Science

基　　金：第三次实验动物资源调查与发展趋势分析(国家科技基础条件平台中心,2022WT28)。

摘　　要：实验动物是支撑生命科学和生物医药等领域科技创新的重要基础科研条件之一。随着科研范式的变革,准确把握科学前沿和国家重大需求,进一步凝练实验动物资源创制与发展中的难点和疑点,对加快推动实验动物新品种/新品系开发和动物模型创制与发展具有重要意义。本文梳理了我国实验动物资源建设和应用情况,就应对新形势下的科研范式变革中存在的主要问题进行了深入探讨,展望了我国实验动物资源发展新动向,以期为实验动物新资源研究开发提供新视角。Laboratory animals are one of the important basic research conditions that support technological innovation in fields such as life sciences and biomedicine.With the transformation of scientific research paradigms,accurately grasping the forefront of science and major national needs,further refining the difficulties and doubts in the creation and development of laboratory animal resources,is of great significance for accelerating the development of new varieties/strains of laboratory animals and animal model creation and development.The paper reviews the construction and application of laboratory animal resources in China,and deeply explores the main problems in responding to the transformation of scientific research paradigms under the new situation.It also looks forward to new trends in the development of experimental animal resources in China,in order to provide a new perspective for the research and development of new experimental animal resources.

关 键 词：实验动物 动物模型 科研范式 问题凝练 创新思维 新视角 

分 类 号：Q95-3[生物学—动物学]