Rpd3S meets the nucleosome  

作　　者：Michael J.Carrozza Jerry L.Workman 

机构地区：[1]Department of Biology,New York University,New York,NY,USA [2]Stowers Institute for Medical Research,Kansas City,MO,USA

出　　处：《Cell Research》2024年第1期1-2,共2页细胞研究（英文版）

摘　　要：Two recent reports in Cell Research present cryo-electron microscopy structures of the Rpd3S HDAC complex bound to the nucleosome.These structures provide novel insight into the binding properties of the Rpd3S subunits Sin3,Rco1 and Eaf3 to DNA and Rco1 and Eaf3 to unmodified H3K4 and methylated H3K36,respectively,and also provide a fascinating look at the unique properties of Rpd3 in recognizing specific acetylated lysines for deacetylation in the context of Rpd3S.

关 键 词：INSIGHT PROPERTIES MODIFIED 

分 类 号：Q2[生物学—细胞生物学]