维生素D与肾结石风险相关性的研究进展  

Research progress on the relationship between risk of kidney calculi and vitamin D

作　　者：唐海啸 赵萱 黄云腾[1] Tang Haixiao;Zhao Xuan;Huang Yunteng(Department of Urology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;Department of Clinical Nutrition,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院泌尿外科,上海200092 [2]上海交通大学医学院附属新华医院临床营养科,上海200092

出　　处：《中华泌尿外科杂志》2024年第2期154-156,共3页Chinese Journal of Urology

摘　　要：肾结石是泌尿外科最常见的疾病之一。补充维生素D可促进肠道吸收钙, 并增加尿钙排泄和肾结石形成的风险。但有研究结果表明, 普通人群补充维生素D并没有患肾结石的风险。因此, 摄入维生素D是否会导致肾结石尚无定论。本文对维生素D的概况及其与肾结石风险相关性的基础研究、临床研究和机制研究作一综述, 当联合服用维生素D和钙补充剂时, 应考虑可能增加肾结石形成的潜在风险。Kidney calculi are one of the most common diseases in urology.Vitamin D supplementation can promote intestinal absorption of calcium,and increase the risk of urinary calcium excretion and kidney calculi formation.However,some studies have shown that vitamin D supplementation in the general population was not associated with the risk of kidney calculi.Therefore,whether taking vitamin D may lead to kidney calculi is still a focus issue.This article mainly reviewed the overview of vitamin D and the basic,clinical and mechanistic studies on the relationship between vitamin D and risk of kidney calculi,and proposed that,when vitamin D and calcium supplements were taken in combination,the potential risk of kidney calculi formation should be considered.

关 键 词：维生素D 肾结石 高钙尿 维生素D_(3)24-羟化酶 

分 类 号：R692.4[医药卫生—泌尿科学]