宽胸气雾剂对冠心病患者PCI术后生活质量的影响  

Effect of broad chest aerosol on quality of life in patients with coronary heart disease after PCI

作　　者：刘怀莉[1] 张秋实[1] 谢晓林[1] 刘路平[1] 胡华伟 LIU Huaili;ZHANG Qiushi;XIE Xiaolin(Department of Cardiovascular Diseases,Hangzhou Third People's Hospital,Hangzhou310009,CHINA)

机构地区：[1]杭州市第三人民医院心内科,浙江310009

出　　处：《江苏医药》2024年第2期133-136,共4页Jiangsu Medical Journal

基　　金：浙江省医药卫生计划项目(2020KY724);杭州市生物医药和健康产业发展扶持科技专项(2021WJCY317)。

摘　　要：目的探讨宽胸气雾剂对冠心病患者经皮冠状动脉介入治疗(PCI)术后生活质量的影响。方法行PCI的冠心病患者60例,根据术后治疗方法不同分为宽胸气雾剂组和对照组,每组30例。两组患者PCI术后均服用冠心病常规用药,宽胸气雾剂组在此基础上加用宽胸气雾剂,每天3次,每次2喷,治疗3个月。于治疗前、治疗1个月和3个月采用健康状况调查问卷(SF-36)和西雅图心绞痛量表(SAQ)评价患者生活质量。结果治疗1个月和3个月,宽胸气雾剂组SF-36评分和SAQ评分高于治疗前,且治疗3个月时的SF-36评分和SAQ评分高于治疗1个月(P<0.05)。治疗1个月和3个月,宽胸气雾剂组SF-36中生理机能、躯体疼痛、活力、情感智能和精神健康评分均高于对照组(P<0.05)。治疗3个月,宽胸气雾剂组SF-36中生理职能、总体健康和社会功能评分高于对照组(P<0.05)。治疗1个月和3个月,宽胸气雾剂组SAQ中躯体活动受限程度、心绞痛稳定状态、治疗满意程度和疾病认知程度评分高于对照组(P<0.05)。治疗3个月,宽胸气雾剂组SAQ中心绞痛发作频率评分高于对照组(P<0.05)。结论在常规治疗基础上加用宽胸气雾剂能有效控制冠心病患者PCI术后心绞痛发作频率,明显改善患者生活质量。Objective To investigate the effect of broad chest aerosol on the quality of life in the patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods Sixty patients with coronary heart disease underwent PCI were randomly divided into two groups of A and B with 30cases each.The patients of two groups received routine medication for coronary heart disease after PCI and those of group A were additionally treated with broad chest aerosol two sprays a time,three times per day for 3months.The quality of life was evaluated using 36-item short-form(SF-36)and Seattle angina questionnaire(SAQ)before treatment(T0),one month(T1)and 3 months(T2)during treatment.Results SF-36scores and SAQ scores at T1and T2were higher than those at T0in group A,which at T2were higher than those at T1(P<0.05).The SF-36scores of physiological function,physical pain,vitality,emotional intelligence and mental health at T1and T2 were higher in group A than those in group B(P<0.05).The SF-36scores of physiological competency,general health and social function at T2in group A were higher than those in group B(P<0.05).The SAQ scores of physical activity limitation,stable angina status,treatment satisfaction and disease cognition at T1and T2were higher in group A than those in group B(P<0.05).The SAQ score of angina pectoris attack frequency at T2was higher in group A than that in group B(P<0.05).Conclusion On the basis of conventional treatment,the additional treatment of broad chest aerosol can effectively control the frequency of angina pectoris in the patients with coronary heart disease after PCI,and improve the quality of life.

关 键 词：冠心病 生活质量 宽胸气雾剂 

分 类 号：R541[医药卫生—心血管疾病]