主动脉内球囊反搏对急性重症心肌炎的疗效及对心功能和心肌酶谱等的影响  

Effect of intra-aortic balloon counterpulsation on acute severe myocarditis and influence of cardiac function and myocardial enzyme

作　　者：赵玉娜 肖莉丽[1] 高文萍 吴蒙蒙 ZHAO Yu-na;XIAO Li-li;GAO Wen-ping;WU Meng-meng(Cardiac Care Unit,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院心内CCU,郑州450052

出　　处：《医药论坛杂志》2024年第2期153-156,160,共5页Journal of Medical Forum

摘　　要：目的探究急性重症心肌炎患者经主动脉内球囊反搏(intra-aortic balloon pump,IABP)改善心肾功能的应用价值。方法将2021年9月至2022年8月至郑州大学第一附属医院就诊的72例重症急性心肌炎患者纳入研究,以治疗方法不同分组,分为对照组和观察组各36例,对照组实施常规基础治疗,观察组实施主动脉内球囊反搏治疗。比较两组心肾功能变化以及临床疗效。结果①观察组治疗后显示,肾小球滤过率(eGFR)及血肌酐水平为(45.84±11.23)mL/min及(115.92±18.97)μmmol/L,低于对照组,24小时尿量(987.67±29.86)mL,高于对照组(P<0.05);②观察组治疗后左室舒张末期容积(LVEDV)水平(51.67±4.22)mm,低于对照组,左室射血分数(LVEF)指标(47.26±3.22)%,高于对照组(P<0.05);③观察组干预后整体有效率97.22%,高于对照组的75.00%,差异有统计学意义(P<0.05);④观察组治疗后Mb、CK-MB、hs-cTn水平分别为(80.63±4.12)g/L、(25.73±6.35)U/L及(0.20±0.04)ng/mL,均低于对照组,差异有统计学意义(P<0.05)。结论临床可以借助主动脉内球囊反搏方式对急性重症心肌炎患者展开积极治疗,不仅可以对其肾功能、心功能进行有效改善,同时还可以提高整体治疗有效率,应用价值显著,值得推广。Objective To explore the application value of intraaortic balloon counterpulsation in improving cardiac and renal function in patients with acute severe myocarditis.Methods A total of 72 patients with severe acute myocarditis who visited the First Affiliated Hospital of Zhengzhou University from September 2021 to August 2022 were included in the study.They were divided into control group and observation group with 36 cases in each group according to different treatment methods.The control group received routine basic treatment,and the observation group received intra-aortic balloon counterpulsation treatment.The cardiac and renal function changes and clinical efficacy of the two groups were compared.Results①After treatment,eGFR and serum creatinine levels in the observation group were(45.84±11.23)mL/min and(115.92±18.97)μmmol/L,lower than those in the group control,and 24-hour urine volume was(987.67±29.86)mL,higher than control group(P<0.05).②LVEDV level in observation group was(51.67±4.22)mm lower than that group control,and LVEF in⁃dex was(47.26±3.22)%higher than control group(P<0.05).③The overall effective rate of the observation group was 97.22%,higher than that of the control group(75.00%)(P<0.05).④Treatment after,levels of hs-cTn CK-MB and Mbin observation group were(80.63±4.12)g/L,(25.73±6.35)U/L and(0.20±0.04)ng/mL,respectively,lower than that of control group(P<0.05).Conclusion Intra-aortic balloon counterpulsation can be used to actively treat patients with acute severe myocarditis,which can not only effectively improve their renal function and cardiac function,but also improve the overall treatment efficiency,which has significant application value and is worth promoting.

关 键 词：重症急性心肌炎 主动脉内球囊反搏 心肾功能 临床疗效 

分 类 号：R542.2[医药卫生—心血管疾病]