急诊外科创伤手术患者给予抗感染治疗的效果分析  

Effect of Anti-infective Therapy on Patients Undergoing Emergency Surgical Trauma

作　　者：韦登贵 Wei Dengui(Department of Emergency,Guangxi Zhuang Autonomous Region Jiangbin Hospital,Nanning 530000,Guangxi Zhuang Autono-mous Region,China)

机构地区：[1]广西壮族自治区江滨医院急诊科,广西壮族自治区南宁530000

出　　处：《中外医药研究》2024年第1期60-62,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:观察急诊外科创伤手术患者给予抗感染治疗的效果。方法:选取2022年1月—2023年1月于广西壮族自治区江滨医院急诊科进行急诊外科创伤手术的患者90例为研究对象,根据随机数字表法分为对照组与观察组,各45例。对照组给予常规消毒治疗,观察组在对照组基础上给予抗感染治疗。比较两组炎性因子水平、伤口细菌定量、伤口微循环状况的变化,并观察两组伤口愈合情况。结果:治疗后,两组白细胞介素-8、C反应蛋白水平均降低,观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组伤口细菌定量水平均降低,观察组低于对照组,差异有统计学意义(P<0.05);治疗后,两组伤口血流量、经皮氧分压均升高,观察组高于对照组,差异有统计学意义(P<0.05)。观察组A级占比高于对照组,C级占比低于对照组,差异有统计学意义(P<0.05)。结论:临床对急诊外科创伤手术患者给予抗感染治疗可改善炎性因子水平、伤口微循环状况,降低伤口细菌定量,促进伤口愈合。Objective:To observe the effect of anti-infection therapy on patients undergoing emergency surgical trauma.Methods:A total of ninety patients undergoing emergency surgical trauma surgery in the emergency department of Guangxi Zhuang Autono⁃mous Region Jiangbin Hospital from January 2022 to January 2023 were selected as the study objects,and were divided into con⁃trol group and observation group according to random number table method,with forty-five cases in each group.The control group was given routine disinfection treatment,and the observation group was given anti-infection treatment on the basis of the control group.The changes of inflammatory factors,wound bacteria quantification and wound microcirculation were compared between the two groups,and the wound healing was observed between the two groups.Results:The levels of interleukin-8 and C-reactive pro⁃tein were decreased in both groups,and the observation group was lower than the control group,the difference was statistically sig⁃nificant(P<0.05);After treatment,the quantitative level of wound bacteria in both groups was decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05);After treatment,wound blood flow and percutaneous oxygen partial pressure were increased in both groups,and the observation group was higher than the control group,the difference was statistically significant(P<0.05);The proportion of grade A in the observation group was higher than that in the control group,and the proportion of grade C was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Anti-infective treatment for emergency surgical trauma patients can improve the level of inflammatory fac⁃tors,wound microcirculation,reduce the amount of wound bacteria,and promote wound healing.

关 键 词：急诊外科创伤手术 常规消毒 甲硝唑片 抗感染 伤口愈合 

分 类 号：R619.3[医药卫生—外科学]