经尿道前列腺等离子电切术治疗高危良性前列腺增生的疗效及对患者残余尿量、最大尿流率影响研究  

The efficacy of Transurethral Plasmakinetic Resection of Prostate in the Treatment of High-risk Benign Prostatic Hyperplasia and its Influence on Residual Urine Volume and Maximum Urinary Flow Rate

作　　者：时文龙 SHI Wenlong(People’s Hospital of Wangmo County,Wangmo 552300,Guizhou,China)

机构地区：[1]望谟县人民医院,贵州望谟552300

出　　处：《现代诊断与治疗》2023年第21期3168-3170,3216,共4页Modern Diagnosis and Treatment

摘　　要：目的探究经尿道前列腺等离子电切术治疗高危良性前列腺增生的效果。方法选取收治的50例高危良性前列腺增生患者,在完善术前常规辅助检查的前提下,均行经尿道前列腺等离子电切术治疗,给予硬脊膜外麻醉,术后安置导尿管,行膀胱冲洗。分析患者手术指标(手术时间、术中失血量、膀胱冲洗时间、尿管留置时间)及治疗前后疼痛介质变化[前列腺素E2(PGE2)、P物质(SP)]、尿道功能指标变化[最大尿流率(Qmax)、残余尿量(RU)]。结果患者均顺利完成经尿道前列腺等离子电切术治疗,手术时间为(75.38±6.47)min、术中失血量为(148.48±46.35)mL、膀胱冲洗时间为(2.16±0.21)d,尿管留置时间为(5.21±0.54)d。术后24 h,患者PGE2、SP水平均比术前显著下降(P<0.05)。术后3个月,患者Qmax均比术前显著上升,RU均比术前显著下降(P<0.05)。结论高危良性前列腺增生接受经尿道前列腺等离子电切术治疗具有显著疗效,可减轻手术创伤,加快术后恢复,缓解术后疼痛,有效保护尿道功能。Objectives To explore the effect of transurethral plasmakinetic resection of prostate in the treatment of high-risk benign prostatic hyperplasia.Methods A total of 50 patients with high-risk benign prostatic hyperplasia admitted to our hospital were selected.On the premise of improving the preoperative routine auxiliary examination,transurethral plasmakinetic resection of prostate was performed.Peridural anesthesia was given,urinary catheter was placed after operation,and bladder irrigation was performed.The operation indexes(operation time,intraoperative blood loss,bladder irrigation time,catheter indwelling time)and the changes of pain mediators[prostaglandin E2(PGE2),substance P(SP)]and the changes of urethral function indexes[maximum urinary flow rate(Qmax),residual urine volume(RU)]before and after treatment were analyzed.Results Transurethral plasmakinetic resection of prostate were successfully completed in all patients.The operation time was(75.38±6.47)min,the intraoperative blood loss was(148.48±46.35)mL,the bladder irrigation time was(2.16±0.21)d,and the catheter indwelling time was(5.21±0.54)d.At 24 h after operation,the levels of PGE2 and SP in patients were significantly lower than those before operation(P<0.05).At 3 months after operation,the Qmax of the patients was significantly higher than that before operation,and the RU was significantly lower than that before operation(P<0.05).Conclusions Transurethral plasmakinetic resection of prostate is effective in the treatment of high-risk benign prostatic hyperplasia,which can reduce surgical trauma,accelerate postoperative recovery,relieve postoperative pain,and effectively protect urethral function.

关 键 词：经尿道前列腺等离子电切术 高危 良性前列腺增生 

分 类 号：R697.32[医药卫生—泌尿科学]