2016—2022年北京市通州区60岁及以上老年人群肺结核流行特征及治疗转归分析  

Analysis of the epidemiological characteristics and treatment outcomes of pulmonary tuberculosis aged≥60 years old in Tongzhou District of Beijing,2016-2022 Yang

作　　者：杨超[1] 王晶[1] 杨朝辉 高汉青 Chao;Wang Jing;Yang Chaohui;Gao Hanqing(Institute of Tuberculosis Prevention and Control,Tongzhou District Center for Disease Prevention and Control,Beijing 101100,China;School of Public Health,Hebei Medical University,Shijiazhuang 050011,China)

机构地区：[1]北京市通州区疾病预防控制中心结核病防治所,北京101100 [2]河北医科大学公共卫生学院,石家庄050011

出　　处：《中国防痨杂志》2024年第4期403-410,共8页Chinese Journal of Antituberculosis

摘　　要：目的:分析2016—2022年北京市通州区60岁及以上老年人群肺结核流行特征及治疗转归情况,为通州区制定老年结核病防治策略提供参考。方法:通过“中国疾病预防控制信息系统”子系统“结核病信息管理系统”收集2016—2022年北京市通州区所有登记管理的60岁及以上老年活动性肺结核患者相关临床信息,包括病案信息、诊疗情况、实验室检查等,运用描述性统计方法分析患者特征和治疗转归,应用季节指数对时间序列进行季节效应分析。结果:2016—2022年,通州区共登记管理活动性肺结核患者4208例,其中,60岁及以上老年肺结核患者963例(22.88%),占比从2016年的22.75%(157/690)上升至2022年的28.06%(142/506),呈上升趋势(χ_(趋势)^(2)=5.749,P=0.016)。老年肺结核患者登记率[53.18/10万(963/181.08万)]明显高于全人群[37.67/10万(4208/1117.14万)],且分别从2016年的82.81/10万(157/18.96万)和50.07/10万(690/137.80万)下降至2022年的43.80/10万(142/32.42万)和27.45/10万(506/184.31万),均呈下降趋势(χ_(趋势)^(2)=10.266,P=0.001;χ_(趋势)^(2)=52.560,P<0.001)。老年患者病原学阳性率[53.27%(513/963)]和0月序痰涂片阳性率[30.22%(291/963)]均明显高于非老年患者[38.34%(1244/3245)和18.86%(612/3245)],差异均有统计学意义(χ^(2)=68.534,P<0.001;χ^(2)=56.844,P<0.001)。老年肺结核患者以男性[68.95%(664/963)]、60~69岁[48.81%(470/963)]、被动发现[90.24%(869/963)]、综合医院转诊[81.83%(788/963)]为主;平均就诊延迟率为40.08%(386/963)。老年肺结核流行期为每年的6~9月,季节指数分别为127.15%、103.47%、134.63%、102.22%。总体成功治疗率为84.29%(692/821),且从2016年的82.80%(130/157)上升至2021年的90.78%(128/141),呈上升趋势(χ_(趋势)^(2)=4.359,P=0.026);其中,女性成功治疗率[88.45%(222/251)]高于男性[82.46%(470/570)],低龄组成功治疗率[89.63%(363/405)]高于中龄组[82.44%(216/262)]和高龄组[73.38%(113/154)],差异均有统�Objective:To analyze the epidemiological characteristics and treatment outcomes of pulmonary tuberculosis(PTB)in the elderly people(≥60 years old)in Tongzhou District of Beijing from 2016 to 2022,and provide reference for formulating prevention and control strategies in Tongzhou District.Methods:Data information of 4208 patients with active PTB in Tongzhou District of Beijing from 2016 to 2022 were collected from the subsystem“Tuberculosis Management Information System”of the China Information System for Disease Control and Prevention including medical records,diagnosis and treatment information,laboratory examination and so on.Descriptive statistics methods were used to analyze the patients’characteristics,treatment and outcomes.The seasonal indexes were used to analyze the seasonal effects of time series.Results:From 2016 to 2022,a total of 963 elderly cases aged 60 and above were registered in Tongzhou District of Beijing,accounting for 22.88%(963/4208)of the total reported patients in the same period.The proportion increased from 22.75%(157/690)in 2016 to 28.06%(142/506)in 2022,showing an increasing trend year by year(χ_(trend)^(2)=5.749,P=0.016).The registration rate in the elderly people(53.18/100000(963/1810800))was significantly higher than that in the whole population(37.67/100000(4208/11171400)).The registration rate of PTB patients in both the elderly people and the general population declined from 82.81/100000(157/189600)and 50.07/100000(690/1378000)in 2016 to 43.80/100000(142/324200)and 27.45/100000(506/1843100)in 2022,showing declining trends(elderly populationχ_(trend)^(2)=10.266,P=0.001;whole populationχ_(trend)^(2)=52.560,P<0.001).The etiological positive rate(53.27%(513/963))and positive rate of 0-month sequence sputum smear(30.22%(291/963))of elderly patients was significantly higher than that in non-elderly group(38.34%(1244/3245))and(18.86%(612/3245))(etiologically positive rateχ^(2)=68.534,P<0.001;positive rate 0-month sequence sputum smearχ^(2)=56.844,P<0.001).The elderly patie

关 键 词：结核 肺 老年 治疗结果 流行病学研究特征(主题) 

分 类 号：R521[医药卫生—内科学]