中国地方性氟中毒健康教育干预效果的Meta分析  

Meta-analysis on the effect of health education intervention for endemic fluorosis in China

作　　者：王明君 沈洪婷[1] 陈勋[1] 李亚楠[1] 周昕[1] 喇翠玲[1] 张金梅 甘培春[1] 蒲光兰[1] 陈萍[1] 鲁青[1] 朱世玲 张强[1] WANG Mingjun;SHEN Hongting;CHEN Xun;LI Ya'nan;Zhou Xin;LA Cuiling;ZHANG Jinmei;GAN Peichun;PU Guanglan;CHEN Ping;LU Qing;ZHU Shiling;ZHANG Qiang(Qinghai ProvinClal Institute of Endemic Disease Prevention and Control,Xining,Qinghai 810000,China;不详)

机构地区：[1]青海省地方病预防控制所地方病预防控制科,青海西宁810000 [2]青海大学医学部

出　　处：《中国地方病防治》2024年第1期16-19,共4页Chinese Journal of Control of Endemic Diseases

基　　金：第二次青藏高原综合科学考察项目(2019QZKK0607)。

摘　　要：目的系统评价了2000年1月至2022年5月中国地方性氟中毒健康教育干预效果的情况。方法通过检索CNKI、VIP、CBM、WanFangData、Webof Science、PubMed和Cochrane Library数据库,收集有关地方性氟中毒健康教育干预效果的自身前后对照研究或本身为干预对照研究,检索时限均为建库至2022年5月30日。由2名评价员独立阅读筛选文献、提取相关资料,并在评价纳入文献的偏倚风险后,采用RevMan5.4.1软件进行Meta分析。结果共纳入62个研究。Meta分析结果显示,中国地方性氟中毒总体知晓率提高32%[95%CI(35%,29%)]。不同亚组分析结果显示,饮水型地方性氟中毒知晓率提高29%,燃煤污染型地方性氟中毒知晓率提高37%,饮茶型地氟病知晓率提高30%。学生知晓率提高32%,成人知晓率提高31%,僧侣知晓率提高38%。华东、华北、华中、华南、西北、西南、东北知晓率分别提高28%、26%、33%、34%、32%、35%、30%。2007-2010年、2011-2014年、2015-2018年、2019年至2022年5月分别提高38%、31%、29%、35%。干预前知晓率在[20%,30%)以及[30%,40%)范围提升最高,分别为53%[95%CI(79%,27%)]和54%[95%CI(59%,48%)]。结论健康教育可以有效提高地方性氟中毒的知晓率,对地方性氟中毒的防治具有积极作用。Objective To systematically evaluate the effect of health education intervention on endemic fluorosis in China from January 2000 to May 2022.Methods CNKI,VIP,CBM,Wanfang Data databases,Web of Science,PubMed and Cochrane Library databases were searched by computer to collect self before and after control studies or intervention control studies on the effect of health education on endemic fluorosis.The retrieval time limit was from the establishment of the database to May 30,2022.Two researchers independently read and screened the literature,extracted relevant data,and evaluated the bias risk of the included literature.Then,revman 5.4.1 software was used for meta-analysis.Results A total of 62 studies were included.Meta analysis showed that the overall awareness rate of endemic fluorosis in China increased by 32%[95%CI(35%,29%)].Subgroup analysis showed that the awareness rate of drinking water endemic fluorosis increased by 29%,that of coal-burning endemic fluorosis increased by 37%,and that of drinking tea-drinking type fluorosis increased by 30%.Students'awareness rate increased by 32%,adults'awareness rate increased by 31%,and monks'awareness rate increased by 38%.The awareness rates in East China,North China,Central China,South China,Northwest,Southwest and Northeast China increased by 28%,26%,33%,34%,32%,35%and 30%respectively.From 2007 to 2010,from 2011 to 2014,from 2015 to 2018,and from 2019 to May 2022,it increased by 38%,31%,29%and 35%respectively.Before the intervention,the awareness rate of[20%,30%)and[30%,40%)increased the most,53%[95%CI(79%,27%)]and 54%[95%CI(59%,48%)] respectively.Conclusion Health education can effectively improve the awareness rate of endemic fluorosis,and health education plays a positive role in the prevention and treatment of endemic fluorosis.

关 键 词：地方性氟中毒 健康教育 干预效果 META分析 

分 类 号：R599.9[医药卫生—内科学]