烟酸类药物临床应用研究进展  

Research progress in clinical application of niacin drugs

作　　者：王月 赵紫楠[1] 郭思瑞 徐文峰[1] 金鹏飞[1] 胡欣[1] WANG Yue;ZHAO Zi-nan;GUO Si-rui;XU Wen-feng;JIN Peng-fei;HU Xin(Department of Pharmacy,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Science,Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application(Beijing Hospital),Beijing 100730,China)

机构地区：[1]北京医院药学部,国家老年医学中心,中国医学科学院老年医学研究院,北京市药物临床风险与个体化应用评价重点实验室(北京医院),北京100730

出　　处：《临床药物治疗杂志》2024年第1期13-16,共4页Clinical Medication Journal

基　　金：国家重点研发计划项目(2020YFC2008300)。

摘　　要：广义烟酸是一种人体必需的水溶性B族维生素,可进一步划分为烟酸和烟酰胺,与其他烟酸衍生物统称为烟酸类药物。因作用靶点或释放特性的差别,烟酸类药物在满足营养需求、疾病治疗以及剂量相关不良反应的特性也有所不同。本文对临床常见的几种烟酸类药物的临床应用及不良反应进行总结。Generalized niacin is an essential water-soluble B-vitamin to the human body,which can be further divided into nicotinic acid and nicotinamide,and can be collectively referred to as niacin drugs along with other nicotine derivatives.Due to the different acting targets or release characteristics,the characteristics of these niacin drugs in meeting nutritional re⁃quirements,disease treatment,and dose-related adverse reactions are also different.In this paper,clinical applications and adverse reactions of several common niacin drugs in clinical applications were summarized.

关 键 词：烟酸 烟酰胺 烟酸类药物 临床应用 不良反应 

分 类 号：R978.7[医药卫生—药品]