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作 者:杨加辉 林萌 喻松仁[1] 罗小泉[1] YANG Jiahui;LIN Meng;YU Songren;LUO Xiaoquan(Jiangxi University of Chinese Medicine,Nanchang 330004,China)
机构地区:[1]江西中医药大学,南昌330004
出 处:《中国实验动物学报》2024年第1期80-91,共12页Acta Laboratorium Animalis Scientia Sinica
基 金:江西省科技基础条件平台(20212BCD46005)。
摘 要:目的利用CiteSpace文献计量学软件,本文对KM小鼠的研究现状和热点进行了可视化分析,旨在为国内KM小鼠研究的突破和创新提供依据。方法本文基于中国知网和Web of Science两个数据库,纳入了2004年1月1日~2023年6月10日的3981篇KM小鼠相关文献,分析了其发文量、国家(地区)、机构、作者合作网络、关键词共现、聚类、突现词和英文文献被引情况。结果KM小鼠研究中文文献发文量波动下降,英文文献发文量逐渐上升,国内外对于KM小鼠的研究热度不同。发文最多的3个国家是中国、美国和日本,国内的主要研究机构有中国农业大学、南京中医药大学以及中国科学院等,发文量较多的作者主要是刘慧雯、李光武和赵欣等。国内期刊研究内容主要集中于KM小鼠毒理学、免疫学和生殖学方面,国外期刊研究主要集中于KM小鼠细胞生物学、生理学方面。结论目前,KM小鼠在我国已有80余年的应用与推广历史,主要集中在毒理学、免疫学和生殖学方面研究。KM小鼠虽在实验方面有一定成果,但规范化种群培育、优势研究领域发掘以及动物伦理的进一步推进是未来需要继续解决的问题。Objective The present situation and hotspots of KM mouse research were visualized by CiteSpace software,which provided a reference for breaking through the bottleneck of KM mouse research and finding new ideas in China.Methods A total of 3981 articles were retrieved from CNKI and Web of Science databases from January 1,2004 to June 10,2023,of which the number of publications,countries(regions),institutions,author cooperation network,keyword co-occurrence,clustering,burst words,and cited English literature for analysis.Results The number of documents published in Chinese was decreased and the number of documents published in English was increased gradually in KM mouse research.The three countries with the most published articles were China,the United States,and Japan,where the leading research institutions were the China Agricultural University,Chinese Academy of Sciences,and Nanjing University of Chinese Medicine.The main authors at home and abroad were Liu Weihui,Li Guangwu,and Zhao Xin.The domestic research focused on the toxicology,immunology,and reproduction of KM mouse,and the foreign research focused on the cell biology and physiology of KM mouse.Conclusions KM mouse have been used and popularized in our country for more than 70 years,mainly focusing on toxicology,immunology,and reproduction.Although the use of KM mouse has led tove made allowed some achievements in experiments,certain it is necessary to solve their problems in the future,such as the standardization of population breeding,the discovery of the dominant research fields,and the further promotion of animal ethics,should be resolved.
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