hs-CRP、cTnI、Myo及CK-MB检测在急性心肌梗死诊断中的临床应用价值  

Clinical Value of Hs-CRP, CTnI, Myo and CK-MB in the Diagnosis ofAcute Myocardial Infarction

作　　者：孙思[1] 刘妍 SUN Si;LIU Yan(Department of Clinical Laboratory,Wuzhong People's Hospital,Suzhou,Jiangsu Province,215128 China)

机构地区：[1]苏州市吴中人民医院检验科,江苏苏州215128

出　　处：《系统医学》2024年第2期61-63,71,共4页Systems Medicine

摘　　要：目的 探讨超敏C反应蛋白(Hypersensitive C-reactive Protein, hs-CRP)、肌钙蛋白(Cardiac Troponin I,cTnI)、肌红蛋白(Myoglobin, Myo)、肌酸激酶同工酶(Creatine Kinase Isoenzymes-MB, CK-MB)联合检测诊断急性心肌梗死的价值。方法 选取2020年2月—2023年5月苏州市吴中人民医院收治的75例急性心肌梗死者与75例健康体检者,设为观察组与对照组,比较两组hs-CRP、cTnI、Myo及CK-MB水平,分析联合检测与心梗三项及hs-CRP检测的诊断效能。结果 观察组hs-CRP、cTnI、Myo、CK-MB均高于对照组,差异有统计学意义(P均<0.05)。联合检测诊断准确度97.33%、灵敏度98.67%,高于心梗三项的92.00%、86.67%与hs-CRP的89.33%、80.00%,差异有统计学意义(χ^(2)=6.125、7.111,12.000、14.000,P均<0.05)。结论 急性心肌梗死患者hs-CRP与心梗三项检测值明显升高,联合检测能提高对急性心肌梗死的诊断效能。Objective To investigate hypersensitive C-reactive protein(hs-CRP),cardiac troponin I(cTnI),myoglobin(Myo)and creatine kinase isoenzyme-MB(CK-MB)Value of combined detection in the diagnosis of acute myocardial infarction.Methods A total of 75 patients with acute myocardial infarction and 75 healthy subjects admitted to Wu⁃zhong People's Hospital of Suzhou City from February 2020 to May 2023 were selected as observation group and con⁃trol group.The levels of hs-CRP,cTnI,Myo and CK-MB were compared between the two groups,and the diagnostic efficacy of combined detection,myocardial infarction and hs-CRP detection was analyzed.Results hs-CRP,cTnI,Myo and CK-MB in observation group were higher than those in control group,and the differences were statistically significant(all P<0.05).The diagnostic accuracy and sensitivity of combined detection were 97.33%and 98.67%,which were higher than 92.00%and 86.67%for MI and 89.33%and 80.00%for hs-CRP,and the difference was sta⁃tistically significant(χ^(2)=6.125,7.111,12.000,14.000,all P<0.05).Conclusion Hs-CRP and MI were significantly in⁃creased in patients with acute myocardial infarction,and combined detection could improve the diagnostic efficiency of acute myocardial infarction.

关 键 词：超敏C反应蛋白 肌钙蛋白 肌红蛋白 肌酸激酶同工酶 急性心肌梗死 诊断效能 

分 类 号：R446.1[医药卫生—诊断学]