经鼻持续正压通气治疗早产儿呼吸窘迫综合征的临床效果分析  

Clinical Effect Analysis of Transnasal Continuous Positive Pressure Ventilation in Treatment of Respiratory Distress Syndrome in Preterm Infants

作　　者：周星 朱双燕 刘玲[1] Zhou Xing;Zhu Shuangyan;Liu Ling(Kunming Children's Hospital,Kunming 650000,Yunnan Province,China)

机构地区：[1]昆明市儿童医院,云南昆明650000

出　　处：《中国社区医师》2024年第4期70-72,共3页Chinese Community Doctors

摘　　要：目的:探讨经鼻持续正压通气治疗早产儿呼吸窘迫综合征的临床效果。方法:选取2021年6月—2022年6月昆明市儿童医院收治的呼吸窘迫综合征早产儿92例作为研究对象,以随机数字表法分为两组,各46例。两组均开展肺表面活性物质治疗,在此基础上,对照组采用控制性通气治疗,观察组采用经鼻持续正压通气治疗。比较两组血气指标、临床指标、并发症发生情况与病死率。结果:治疗前,两组pH值、动脉血氧分压(PaO_(2))及动脉血二氧化碳分压(PaCO_(2))比较,差异无统计学意义(P>0.05);治疗后,两组pH值、PaCO_(2)比较,差异无统计学意义(P>0.05),但两组PaCO_(2)均低于治疗前,差异有统计学意义(P<0.05);两组PaO_(2)均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组呼吸机使用时间、用氧时间及住院时间均短于对照组,差异有统计学意义(P<0.001)。观察组并发症总发生率低于对照组,差异有统计学意义(P=0.006);两组病死率比较,差异无统计学意义(P>0.05)。结论:经鼻持续正压通气治疗早产儿呼吸窘迫综合征的临床效果较好,能够改善患儿血气分析指标,促进康复,降低并发症发生率。Objective:To explore the clinical effect of transnasal continuous positive pressure ventilation in treatment of respiratory distress syndrome in preterm infants.Methods:A total of 92 preterm infants with respiratory distress syndrome admitted to Kunming Children's Hospital from June 2021 to June 2022 were selected as the study subjects.They were divided into two groups according to random number table method,with 46 cases in each group.Pulmonary surfactant treatment was performed in both groups.On this basis,the control group used controlled ventilation,and the observation group used transnasal continuous positive pressure ventilation.Blood gas indicators,clinical indicators,complications and mortality were compared between the two groups.Results:Before treatment,there was no significant difference in pH value,arterial partial pressure of oxygen(PaO_(2))and arterial partial pressure of carbon dioxide(PaCO_(2))between the two groups(P>0.05);After treatment,there was no significant difference in pH value and PaCO_(2) between the two groups(P>0.05),but the PaCO_(2) in two groups was lower than that before treatment,and the difference was statistically significant(P<0.05);the PaO_(2) in two groups was higher than that before treatment,and this indicator in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The duration of ventilator use,oxygen use and hospital stay in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.001).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.006).There was no significant difference in the fatality rate between the two groups(P>0.05).Conclusion:Transnasal continuous positive pressure ventilation has good clinical effects in the treatment of respiratory distress syndrome in preterm infants,and can improve blood gas indicators,promote the recovery a

关 键 词：早产儿 呼吸窘迫综合征 经鼻持续正压通气 

分 类 号：R722.1[医药卫生—儿科]