通便贴处方改进前后制备方法和临床效果观察  

Preparation Method and Clinical Observation of Laxative Patch Prescription Before and After Improvement

作　　者：吴显珍 卢春茜 WU Xianzhen;LU Chunqian(Department of Pharmacy,Miyun District Traditional Chinese Medicine Hospital in Beijing,Beijing 101500,China;Department of Internal Medicine,Miyun District Traditional Chinese Medicine Hospital in Beijing,Beijing 101500,China)

机构地区：[1]北京市密云区中医医院药剂科,北京101500 [2]北京市密云区中医医院内科,北京101500

出　　处：《中国卫生标准管理》2024年第5期146-149,共4页China Health Standard Management

摘　　要：目的比较北京市密云区中医医院自制通便贴处方改进前后的疗效和安全性。方法本研究采用回顾性病例研究设计,选取2020年4月—2021年3月使用通便贴患者49例,设为对照组;2021年4月—2022年3月使用通便贴1号患者45例作为研究对象,设为观察组,统计治疗效果及不良反应发生情况,并进行比较分析。结果治疗前后,2组便秘主要症状评分比较,差异无统计学意义(P>0.05)。观察组总有效率为95.6%,高于对照组的91.8%,差异无统计学意义(P>0.05)。观察组不良反应发生率为2.2%,低于对照组的18.4%,差异有统计学意义(P<0.05)。结论改进后的通便1号处方与原处方通便贴处方,在疗效没有降低的前提下,降低不良反应的发生率,增加了用药安全性,提高了便秘治疗的综合效益。Objective To compare the efficacy and safety of improvement in Miyun District Traditional Chinese Medicine Hospital in Beijing self-made laxative patch prescription before and after.Methods This study adopts a retrospective case study design,selecting a total of 49 cases who used toilet patches from April 2020 to March 2021 as the control group;from April 2021 to March 2022,a total of 45 cases using No.1 toilet patch were selected as the study subjects,and set as the observation group.The treatment effect and incidence of adverse reactions were statistically analyzed and compared.Results Before and after treatment,a comparison of the primary symptoms scores of the two groups with constipation showed no significant statistical difference(P>0.05).The total effectiveness rate of the observation group was 95.6%,which was higher than the 91.8%of the control group,yet this difference was not statistically significant(P>0.05).The incidence rate of adverse reactions in the observation group was 2.2%,which was lower than the 18.4%of the control group,and this difference was statistically significant(P<0.05).Conclusion The improved laxative No.1 prescription and the original laxative patch prescription have reduced the incidence of adverse reactions,increased medication safety,and improved the comprehensive benefits of constipation treatment without reducing the efficacy.

关 键 词：穴位贴敷 便秘 疗效 不良反应 制备方法 用药安全 

分 类 号：R442[医药卫生—诊断学]