缺血性脑卒中介入治疗麻醉中应用盐酸右美托咪定的临床价值分析  

Analysis of clinical value of dexmedetomidine hydrochloride in anesthesia of interventional therapy for ischemic stroke

作　　者：赵立华[1] ZHAO Li-hua(Huantai County Maternal and Child Health Center,Zibo 256400,China)

机构地区：[1]山东省淄博市桓台县妇幼保健院,256400

出　　处：《中国实用医药》2024年第5期93-95,共3页China Practical Medicine

摘　　要：目的 分析缺血性脑卒中介入治疗麻醉中应用盐酸右美托咪定的临床价值。方法 80例接受介入手术治疗的缺血性脑卒中患者,按照计算机表法分为对照组以及实验组,每组40例。两组采用相同的麻醉诱导方法 ,对照组采用间断推注顺阿曲库铵联合七氟烷吸入麻醉,实验组应用盐酸右美托咪定麻醉。比较两组不同时间生命体征、麻醉效果、不良反应发生情况。结果 麻醉后及手术后,实验组心率(84.25±7.16)、(82.32±6.28)次/min以及平均动脉压(92.24±3.58)、(90.17±5.24)mm Hg(1 mm Hg=0.133 kPa)均低于对照组的(96.48±6.88)、(86.81±5.77)次/min和(103.11±4.05)、(94.92±5.48)mm Hg,组间存在差异(P<0.05)。实验组麻醉效果总优良率为97.50%,与对照组的82.50%进行比较,实验组更高,组间存在差异(P<0.05)。实验组不良反应发生率2.50%明显低于对照组的20.00%,组间存在差异(P<0.05)。结论 缺血性脑卒中患者进行介入治疗麻醉时应用盐酸右美托咪定的麻醉效果显著,并且不良反应较少,值得在临床中推广应用。Objective To analyze the clinical value of dexmedetomidine hydrochloride in anesthesia of interventional therapy for ischemic stroke.Methods A total of 80 patients with ischemic stroke who receiving interventional therapy were divided into a control group and an experimental group according to the method of computer,each with 40 cases.Both groups were given the same anesthesia induction method,the control group was given intermittent infusion of cisatracurium combined with sevoflurane inhalation,and the experimental group was given dexmedetomidine hydrochloride.The vital signs at different times,anesthetic effects and adverse reactions were compared between the two groups.Results After anesthesia and surgery,the heart rate of the experimental group were(84.25±7.16),(82.32±6.28)beats/min,and the mean arterial pressure were(92.24±3.58),(90.17±5.24)mm Hg(1 mm Hg=0.133 kPa),which were lower than(96.48±6.88),(86.81±5.77)beats/min and(103.11±4.05),(94.92±5.48)mm Hg of the control group,and there were differences between groups(P<0.05).The total excellent and good rate of anesthesia in the experimental group was 97.50%,which was higher than 82.50%in the control group,and there was difference between groups(P<0.05).The incidence of adverse reactions in the experimental group was 2.50%,which was significantly lower than 20.00%in the control group,and there was difference between groups(P<0.05).Conclusion The application of dexmedetomidine hydrochloride in the interventional anesthesia of ischemic stroke patients has significant anesthetic effect and less adverse reactions,which is worth popularizing and applying in clinical practice.

关 键 词：缺血性脑卒中 介入治疗 麻醉 盐酸右美托咪定 

分 类 号：R614[医药卫生—麻醉学]